Abstract: Provided are nine multi-target polypeptides of an opioid and a neuropeptide FF receptor, where an amino acid is replaced on the basis of opioid peptide biphalin- and NPFF-based chimeric peptide BN-9, and acquired are the multi-target polypeptides capable of concurrently activating various opioid and NPFF system receptors.
Type:
Grant
Filed:
April 13, 2017
Date of Patent:
November 9, 2021
Assignee:
Shanghai Tianci Life Science Development Co., Ltd.
Inventors:
Rui Wang, Quan Fang, Zilong Wang, Biao Xu