Abstract: Provided is a fusion protein, which comprises human papillomavirus E7 antigen, virus capsid protein and molecular chaperone. Also provided is a macromolecule with immunogenicity aggregated by the fusion proteins. The particle morphology of the macromolecule is different from that of the virus-like particle. The macromolecule can be used for treatment of human papillomavirus relating diseases.
Type:
Grant
Filed:
June 18, 2008
Date of Patent:
June 25, 2013
Assignees:
Shanghai Zerun-Ankegens Biopharmaceutical Company, Ltd., Yunxu CAO