Abstract: Disclosed herein is a method of forming a mold comprising disposing a film having a textured surface on a support; where the support has a shape of an article to be manufactured; pressing the film onto the support to cover a surface of the support; disposing a backing on the film; separating the support from the backing; and molding a material in the backing. Disclosed herein too is a method comprising contacting a first mandrel with a first mold; where the first mold has a textured surface; texturing a surface of the first mandrel with the first mold; disposing the first mandrel in a die; disposing a first material in the die to contact the first mandrel; imparting a texture from the surface of the first mandrel onto the material to form a second mold; and disposing a texture from the second mold onto a second material; where the second material is different from the first material.

Abstract: Disclosed herein is a method comprising transporting a conduit and a template through a guide tube; the template being disposed on an outer surface of the conduit between the conduit and the guide tube; and transferring a texture from the template to the conduit as the conduit and the template are transported through the guide tube. Disclosed herein too is an apparatus comprising a guide tube; the guide tube being operative to facilitate a transfer of a pattern from a template to a conduit; a first feed spool and a first take-up spool for feeding the conduit through the guide tube and for taking up the conduit after it has travelled through the guide tube respectively; and a second feed spool and a second take-up spool for feeding the template through the guide tube and for taking up the template after it has travelled through the guide tube respectively.

Abstract: Disclosed herein is a multilayered tape comprising a first layer; where the first layer comprises a first surface and second surface; the first surface of the first layer having a surface texture; a second layer; the second layer having a first surface and a second surface; where the first surface of the second layer is closer to the second surface of the first layer than the second surface of the second layer; where the second surface of the second layer contains at least one partition that is parallel to a longitudinal direction of the multilayered tape.

Abstract: Disclosed herein is a multilayered wound dressing comprising a first layer; the first layer including channels that facilitate neovascularization of a wound; and a second layer in contact with the first layer, the second layer having the same or different chemical composition as the first layer; where the second layer comprises at least one surface that has a texture and the direction of the texture is operative to facilitate cell orientation and growth. A method includes forming a first layer of a polymeric material; forming a second layer of the same polymeric material as the first layer on the first layer; and forming a textured surface of the second layer of the same polymeric material as the first layer, the textured surface being operative to facilitate directional cell growth when used in a wound dressing, where the first layer and the second layer are formed using an additive manufacturing process.

Abstract: Disclosed herein is a die assembly comprising a first attachment block having a passage, an inlet port and an exit port; where the passage is operative to transport a molten material from the inlet port to the outlet port; a die; and a conduit; where the conduit comprises a passage that is operative to transport the molten material from the first attachment block to an entry port of the die; where the die comprises a first outer tube; and an extrusion pin that comprises a post and fins; where the extrusion pin is located in the first outer tube using the fins and where the post extends from the fins in a direction away from the entry port of the die; and where the post comprises one or more passages; where at least of these passages open to the atmosphere to provide for pressure equalization; and a travelling template; the template being operative to contact an extrudate that emanates from the die and to transfer a texture to a surface of the extrudate by virtue of pressure applied by a guide tube to the extr

Abstract: An article includes a path that extends across at least a portion of a surface of the article, the path being defined by at least one channel that traverses at least a portion of the surface or a first plurality of spaced features disposed on or in at least a portion of the surface. The first plurality of spaced features are arranged in a plurality of groupings. The groupings of features comprise repeat units, where the spaced features within a grouping are spaced apart at an average distance of about 1 nanometer to about 500 micrometers to define a path that traverses the plurality of spaced features.

Abstract: Disclosed herein is a multilayered article comprising a first layer having a surface texture on a first surface; and a second layer contacting the surface texture on the first layer; where the surface texture comprises a plurality of identical patterns; each pattern being defined by a plurality of spaced apart features attached to or projected into the first surface, at least one spaced apart feature having a dimension of about 1 nanometer to about 1 millimeter, the plurality of features each having at least one neighboring feature having a substantially different geometry, wherein each pattern has at least one feature which is identical to a feature of a neighboring pattern and shares that feature with the neighboring pattern, wherein an average spacing between adjacent spaced apart features is about 1 nanometer to about 1 millimeter in at least a portion of the first surface, wherein the plurality of spaced apart features are represented by a periodic function.

Abstract: Disclosed herein is a method comprising transporting a conduit and a template through a guide tube; the template being disposed on an outer surface of the conduit between the conduit and the guide tube; and transferring a texture from the template to the conduit as the conduit and the template are transported through the guide tube. Disclosed herein too is an apparatus comprising a guide tube; the guide tube being operative to facilitate a transfer of a pattern from a template to a conduit; a first feed spool and a first take-up spool for feeding the conduit through the guide tube and for taking up the conduit after it has travelled through the guide tube respectively; and a second feed spool and a second take-up spool for feeding the template through the guide tube and for taking up the template after it has travelled through the guide tube respectively.

Abstract: Generally, an intraocular implant having on the external surface a plurality of pattern surface elements disposed in spaced apart relation defining a tortuous pathway adapted to control a flow of fluid or a flow of particles suspended in a fluid or inhibit the growth or migration of cells is provided. In particular, an intraocular implant that is implanted between an intraocular lens and the surface of the posterior capsule of the eye inhibits growth or migration of residual lens epithelial cells after cataract surgery by providing structural barriers to reduce posterior capsule opacification of the eye.

Abstract: An article has a surface topography for resisting bioadhesion of organisms and includes a base article having a surface. A composition of the surface includes a polymer. The surface has a topography comprising a pattern defined by a plurality of spaced apart features attached to or projected into the base article. The plurality of features each have at least one microscale dimension and at least one neighboring feature having a substantially different geometry, wherein neighboring patterns share a common feature. The surface has an optical transmission at 400 nm to 700 nm of equal to or greater than 70%. In one embodiment, the surface can comprise a coating layer disposed on the base article.

Abstract: Generally, an intraocular implant having on the external surface a plurality of pattern surface elements disposed in spaced apart relation defining a tortuous pathway adapted to control a flow of fluid, or a flow of particles suspended in a fluid, or inhibits the growth or migration of cells. In particular, an intraocular implant which implanted between an intraocular lens and the surface of the posterior capsule of the eye inhibits growth or migration of residual lens epithelial cells after cataract surgery by providing structural barriers to reduce posterior capsule opacification of the eye.

Abstract: Disclosed herein is a ventilator text fixture comprising a ventilator port that connects to a ventilator through a breathing circuit; where the ventilator delivers air through the ventilator port to a ventilator test fixture at a rate and pressure that can be controlled by a user to simulate inhalation; an input port; where the input port is in fluid communication with the ventilator port; where the input port permits additional simulated secretions or test liquids to be pumped into the ventilator text fixture; one or more bent supports; a liquid reservoir; where the liquid reservoir is operative to hold test fluids; and one or more tubes; where the one or more tubes are in fluid communication with the ventilator port and the input port via the liquid reservoir; and where the one or more bent supports are operative to mimic an anatomy of the trachea.

Abstract: Generally, an intraocular implant having on the external surface a plurality of pattern surface elements disposed in spaced apart relation defining a tortuous pathway adapted to control a flow of fluid, or a flow of particles suspended in a fluid, or inhibits the growth or migration of cells. In particular, an intraocular implant which implanted between an intraocular lens and the surface of the posterior capsule of the eye inhibits growth or migration of residual lens epithelial cells after cataract surgery by providing structural barriers to reduce posterior capsule opacification of the eye.