Abstract: The present invention relates to a process to create a carbon-nitrogen bond by the reaction of an aromatic compound carrying at least one electro attractive group with one nitrogenous heterocyclic type nucleophile compound. The invention aims, in particular, at a link reaction between an aromatic compound carrying at least one electro attractive group and an imidazole heterocycle type.
Type:
Application
Filed:
August 4, 2006
Publication date:
May 6, 2010
Applicant:
SHASUN PHARMA SOLUTIONS LIMITED
Inventors:
Christelle Mauger, Gerard Mignani, Roland Jacquot
Abstract: A method for acylation of an aromatic compound, comprising reacting an aromatic compound and an acylating agent of the carboxylic acid type, in the presence of a Lewis acid and of a silylated reagent selected from the group consisting of halosilanes and halosiloxanes.
Type:
Application
Filed:
October 28, 2005
Publication date:
June 26, 2008
Applicant:
Shasun Pharma Solutions Limited
Inventors:
Damien Bourgeois, Joel Turconi, Johann Vastra
Abstract: The invention concerns a method for functionalizing a double bond and, more particularly, a double bond bearing a metalloid atom. Said functionalization is produced by the action of perhalogenated sulphonyl chloride on the carbon bearing sulphur in the presence of a free radical initiator, preferably by homolytic cleavage. The invention is useful in organic synthesis.