Patents Assigned to SHEMYAKIN-OVCHINNIKOV INSTITUTE OF BIOORGANIC CHEMISTRY OF THE RUSSIAN ACADEMY OF SCIENCES
  • METHOD FOR ULTRA-HIGH PERFORMANCE SCREENING OF BIOLOGICAL OBJECTS
    Publication number: 20230324306
    Abstract: The invention relates to the field of biotechnology and pharmaceutics. Proposed is a method for ultra-high performance screening of biological objects which is based on microfluidic generation of droplets of a biocompatible water-in-oil-in-water double emulsion, and also a method for producing a monodisperse biocompatible water-in-oil-in-water double emulsion. The invention can be used in diagnosing conditions and diseases in mammals, as well as for investigating biological objects.
    Type: Application
    Filed: January 30, 2023
    Publication date: October 12, 2023
    Applicant: SHEMYAKIN-OVCHINNIKOV INSTITUTE OF BIOORGANIC CHEMISTRY OF THE RUSSIAN ACADEMY OF SCIENCES
    Inventors: Alexander Gabibovich GABIBOV, Ivan Vitalievich SMIRNOV, Stanislav Sergeevich TEREKHOV
  • Method for ultra-high performance screening of biological objects
    Patent number: 11604145
    Abstract: The invention relates to the field of biotechnology and pharmaceutics. Proposed is a method for ultra-high performance screening of biological objects which is based on microfluidic generation of droplets of a biocompatible water-in-oil-in-water double emulsion, and also a method for producing a monodisperse biocompatible water-in-oil-in-water double emulsion. The invention can be used in diagnosing conditions and diseases in mammals, as well as for investigating biological objects.
    Type: Grant
    Filed: March 13, 2018
    Date of Patent: March 14, 2023
    Assignee: SHEMYAKIN-OVCHINNIKOV INSTITUTE OF BIOORGANIC CHEMISTRY OF THE RUSSIAN ACADEMY OF SCIENCES
    Inventors: Alexander Gabibovich Gabibov, Ivan Vitalievich Smirnov, Stanislav Sergeevich Terekhov
  • ARTICLES AND METHODS DIRECTED TO PERSONALIZED THERAPY OF CANCER
    Publication number: 20200400676
    Abstract: Described are methods for providing personalized medicine for the treatment of B cell malignancies including lymphoma. The methods make use of Chimeric Antigen Receptor (CAR) technology.
    Type: Application
    Filed: August 3, 2020
    Publication date: December 24, 2020
    Applicants: OPKO Pharmaceuticals, LLC, The Scripps Research Institute, Shemyakin-Ovchinnikov institute of Bioorganic Chemistry, Russian Academy of Sciences, PJSC Pharmsynthez
    Inventors: Alexey Vyacheslavovich Stepanov, Dmitry Dmitrievich Genkin, Richard A. Lerner, Alexey Anatolievich Belogurov, Alexander Gabibovich Gabibov, Jia Xie
  • ARTICLES AND METHODS DIRECTED TO PERSONALIZED THERAPY OF CANCER
    Publication number: 20200363420
    Abstract: Described are methods for providing personalized medicine for the treatment of B cell malignancies including lymphoma. The methods make use of Chimeric Antigen Receptor (CAR) technology.
    Type: Application
    Filed: August 3, 2020
    Publication date: November 19, 2020
    Applicants: OPKO Pharmaceuticals, LLC, The Scripps Research Institute, Shemyakin-Ovchinnikov institute of Bioorganic Chemistry, Russian Academy of Sciences, PJSC Pharmsynthez
    Inventors: Alexey Vyacheslavovich Stepanov, Dmitry Dmitrievich Genkin, Richard A. Lerner, Alexey Anatolievich Belogurov, Alexander Gabibovich Gabibov, Jia Xie
  • METHOD FOR ULTRA-HIGH PERFORMANCE SCREENING OF BIOLOGICAL OBJECTS
    Publication number: 20200256801
    Abstract: The invention relates to the field of biotechnology and pharmaceutics. Proposed is a method for ultra-high performance screening of biological objects which is based on microfluidic generation of droplets of a biocompatible water-in-oil-in-water double emulsion, and also a method for producing a monodisperse biocompatible water-in-oil-in-water double emulsion. The invention can be used in diagnosing conditions and diseases in mammals, as well as for investigating biological objects.
    Type: Application
    Filed: March 13, 2018
    Publication date: August 13, 2020
    Applicant: SHEMYAKIN-OVCHINNIKOV INSTITUTE OF BIOORGANIC CHEMISTRY OF THE RUSSIAN ACADEMY OF SCIENCES
    Inventors: Alexander Gabibovich GABIBOV, Ivan Vitalievich SMIRNOV, Stanislav Sergeevich TEREKHOV
  • Method for producing a transgenic plant with the aid of
    Patent number: 7947871
    Abstract: The invention relates to an improved method for agrobacterium transformation and regeneration of plants. The inventive method is characterized in that it consists in sequentially preparing, inoculating and co-cultivating explants. The preparation of each subsequent lot of plants is carried out after a time interval for transforming plant cells and forming an induced resistance with respect to abiotic and biotic stresses in a leaf discs, thereby making it possible to reduce a necrosis degree and the number of somaclonal variations of the transgenic plants.
    Type: Grant
    Filed: October 15, 2003
    Date of Patent: May 24, 2011
    Assignee: Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry Russian Academy of Sciences
    Inventors: Konstantin Aleksandrovich Shestibratov, Sergey Vladimirovich Dolgov
  • Method for producing a transgenic plant with the aid of agrobacterium thumefaciens
    Publication number: 20070124835
    Abstract: The invention relates to an improved method for agrobacterium transformation and regeneration of plants. The inventive method is characterized in that it consists in sequentially preparing, inoculating and co-cultivating explants. The preparation of each subsequent lot of plants is carried out after a time interval for transforming plant cells and forming an induced resistance with respect to abiotic and biotic stresses in a leaf discs, thereby making it possible to reduce a necrosis degree and the number of somaclonal variations of the transgenic plants.
    Type: Application
    Filed: October 15, 2003
    Publication date: May 31, 2007
    Applicant: Shemyakin And Ovchinnikov Institute of Bioorganic Chemistry Russian Academy of Sciences
    Inventors: Konstantin Shestibratov, Sergey Dolgov