Patents Assigned to Shenzhen Allucks BioTech Co., Ltd.
  • Construct of tumor-selective recombinant adenovirus, method for preparing the same and use thereof
    Publication number: 20050271622
    Abstract: Disclosed is a recombinant human adenovirus type 5 adenovirus construct, in which a 920-946 nt sequence of ADV5 genome and a 28532-29360 nt sequence of the E3 region are deleted while a foreign cDNA fragment is reversely inserted into the deleted E3 region. A method for preparing the recombinant ADV5 construct is also provided. The construct provided herein presents a tumor-specific replication, tumor-specific expression of the inserted anti-gene and tumor-specific bystander effects, and is suitable for use in tumor therapy.
    Type: Application
    Filed: June 3, 2004
    Publication date: December 8, 2005
    Applicant: Shenzhen Allucks BioTech Co., Ltd.
    Inventors: Jianfeng Zhou, Ding Ma, Yunping Lu, Shixuan Wang, Gang Chen, Qinglei Gao
  • Construct of anti-cancer recombinant adenovirus, method for preparing the same and use thereof
    Publication number: 20050079158
    Abstract: Disclosed is a recombinant human adenovirus type 5 adenovirus construct, in which a fragment in the E1A region of the ADV5 genome and a fragment in the E3 region are deleted while a foreign cDNA fragment is reversely inserted into the deleted E3 region. A method for preparing the recombinant ADV5 construct is also provided. The construct provided herein presents a tumor-specific replication, tumor-specific expression of the inserted anti-gene and tumor-specific bystander effects, and is suitable for use in tumor therapy.
    Type: Application
    Filed: June 3, 2004
    Publication date: April 14, 2005
    Applicant: Shenzhen Allucks BioTech Co., Ltd.
    Inventors: Jianfeng Zhou, Ding Ma, Yunping Lu, Shixuan Wang, Gang Chen, Qinglei Gao