Abstract: A hybrid power supply method, a device and a micro-energy power supply based on micro-energy collection are provided. The method includes: collecting micro-energy and storing the collected micro-energy in an energy storage unit; awakening or starting a system after the energy storage unit reaches a startup power; turning into a power saving mode after the system is started, and switching to a reserve energy storage unit for power supply; supplying the energy acquired by micro-energy collection to the system for data interaction; and making the system turn into the power saving mode after data transmission is completed, and switch to the reserve energy storage unit for power supply. A hybrid power supply mode is adopted, where the environmental energy collection is a main power supply and the chemical battery is an auxiliary power supply, so as to ensure the all-day operation of the device.