Patents Assigned to Shenzhen Institute For Drug Control
  • Patent number: 11710541
    Abstract: A chemical pattern recognition method for evaluating the quality of a traditional Chinese medicine based on medicine effect information, comprising: collecting chemical information of a traditional Chinese medicine sample, obtaining medicine effect information reflecting a clinical therapeutic effect thereof, performing spectrum-effect relationship analysis on the chemical information and the medicine effect information, and obtaining an index significantly related to the medicine effect as a feature chemical index; dividing the traditional Chinese medicine sample into a training set and a test set; using a pattern recognition method to extract a feature variable from samples of the training set by taking the feature chemical index as an input variable; building a pattern recognition model using the feature variable; and substituting feature variable values of samples of the test set into the model, and completing chemical pattern recognition evaluation of the quality of the traditional Chinese medicine.
    Type: Grant
    Filed: December 2, 2019
    Date of Patent: July 25, 2023
    Assignee: SHENZHEN INSTITUTE FOR DRUG CONTROL (SHENZHEN TESTING CENTER OF MEDICAL DEVICES)
    Inventors: Tiejie Wang, Yi Lu, Lijun Wang, Kun Jiang, Yang Wang, Jue Wang, Guo Yin, Yang Huang, Yibao Jin
  • Publication number: 20230017825
    Abstract: A chemical pattern recognition method for evaluating the quality of a traditional Chinese medicine based on medicine effect information, comprising: collecting chemical information of a traditional Chinese medicine sample, obtaining medicine effect information reflecting a clinical therapeutic effect thereof, performing spectrum-effect relationship analysis on the chemical information and the medicine effect information, and obtaining an index significantly related to the medicine effect as a feature chemical index; dividing the traditional Chinese medicine sample into a training set and a test set; using a pattern recognition method to extract a feature variable from samples of the training set by taking the feature chemical index as an input variable; building a pattern recognition model using the feature variable; and substituting feature variable values of samples of the test set into the model, and completing chemical pattern recognition evaluation of the quality of the traditional Chinese medicine.
    Type: Application
    Filed: December 2, 2019
    Publication date: January 19, 2023
    Applicant: SHENZHEN INSTITUTE FOR DRUG CONTROL (SHENZHEN TESTING CENTER OF MEDICAL DEVICES)
    Inventors: Tiejie WANG, Yi LU, Lijun WANG, Kun JIANG, Yang WANG, Jue WANG, Guo YIN, Yang HUANG, Yibao JIN
  • Patent number: 9005986
    Abstract: A method for rapidly measuring melatonin adulteration of Chinese patent medicines and healthcare foods comprises: (1) extracting melatonin added to a Chinese patent medicine or healthcare food by using ethyl acetate; and (2) adding p-dimethylaminocinnamaldehyde to the extracted solution, and observing color. The method is rapid, simple and convenient, has strong specificity, high accuracy, reaction sensitivity, and a wide application range, and is applicable to on-site detection of melatonin adulteration of a Chinese patent medicine or healthcare food.
    Type: Grant
    Filed: July 2, 2012
    Date of Patent: April 14, 2015
    Assignee: Shenzhen Institute For Drug Control
    Inventors: Tiejie Wang, Yi Lu, Lihe Xiao, Xiaoying Guan, Dongqi Han, Guo Yin, Jue Wang, Xueqing Li, Yan Yan