Patents Assigned to Shenzhen Institute of Advanced Technology
  • Patent number: 12223626
    Abstract: A method for denoising an image, an apparatus, and a computer-readable storage medium. The method includes: dividing a to-be-processed image into a plurality of image areas; for each image area, expanding an edge of the image area to obtain an expanded area; wherein the expanded area comprises the image area and an edge area, and the edge area comprises pixels in another image area adjacent to the image area; for each expanded area, performing denoising processing on the expanded area through a preset algorithm to obtain a denoised expanded area; wherein the denoised expanded area comprises a denoised image area and a denoised edge area; and abandoning the denoised edge area in each denoised expanded area, and retaining and combining all the denoised image areas to form a denoised image.
    Type: Grant
    Filed: April 29, 2022
    Date of Patent: February 11, 2025
    Assignee: SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGY
    Inventors: Rongliang Chen, Xiaochuan Cai
  • Patent number: 12224057
    Abstract: A medical image processing method and processing apparatus, and a computer readable storage medium. The method includes: obtaining a to-be-processed image; performing a feature extraction on the to-be-processed image to obtain a corresponding feature image; and re-determining a pixel value of each pixel in the to-be-processed image based on first information and second information of a corresponding pixel in the feature image, and processing the to-be-processed image; wherein the first information is information of a pixel adjacent to the corresponding pixel in the features image, and the second information is information of a pixel that is not adjacent to and is similar to the corresponding pixel in the features image.
    Type: Grant
    Filed: May 8, 2022
    Date of Patent: February 11, 2025
    Assignee: SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGY
    Inventors: Na Zhang, Hairong Zheng, Xin Liu, Zhanli Hu, Zhiyuan Huang, Dong Liang
  • Publication number: 20250040827
    Abstract: A multichannel endorectal coil for prostate MRI, a system, and a working method. The coil comprises a support body provided with a winding curved surface, a plurality of first endorectal coils (1, 2, 3) wrapped around the surface of the support body, and a second endorectal coil stacked on the plurality of first endorectal coils (1, 2, 3); wherein two adjacent first endorectal coils (1, 2, 3) are decoupled by means of partial overlapping, and two non-adjacent first endorectal coils (1, 2, 3) are decoupled by providing a shared capacitor (5); the second endorectal coil comprises a first coil section and a second coil section which are in intersecting connection with one another, the first coil section and the second coil section are arranged symmetrically, and no electrical connection exists at the intersection thereof. The invention increases the number of channels, and further achieves better high-resolution imaging capabilities.
    Type: Application
    Filed: October 21, 2024
    Publication date: February 6, 2025
    Applicant: SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGY CHINESE ACADEMY OF SCIENCES
    Inventors: Ye LI, Zhiguang MO, Xiaoping ZHANG, Huageng LIANG, Chao LUO, Qiaoyan CHEN, Changjun TIE, Qi CAO, Wen XIAO
  • Publication number: 20250038393
    Abstract: The invention relates to a directional coupler, coupling high power and low power is used to replace existing two high-power directional couplers, thus reducing the cost and reducing the insertion loss of high-power radio frequency channels. The directional coupler cooperates with a control conditioning board, a splitter, a multi-path radio frequency power amplifier and a combiner to form the radio frequency power amplifier system, and the system is connected to a spectrometer; on one hand, by using a standard signal output by the spectrometer and a feedback signal of the directional coupler, nonlinearity caused by the power amplifier is corrected to achieve magnet-free linear radio frequency power amplification and anomaly protection; and on the other hand, the spectrometer can be used for monitoring the output power of the directional coupler and monitoring antenna matching, so as to provide dual protection for the radio frequency power amplifier system.
    Type: Application
    Filed: October 9, 2024
    Publication date: January 30, 2025
    Applicant: SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGY
    Inventors: Hairong ZHENG, Xinwei RONG, Ye LI, Jiasheng WANG, Jifeng CHEN, Xing YANG
  • Publication number: 20250031975
    Abstract: A temperature measuring method and apparatus based on creatine chemical exchange saturation transfer (CEST) imaging. The method comprises the following steps: (1) performing creatine CEST imaging on a creatine phantom, and analyzing a chemical shift of creatine relative to water in the creatine phantom; (2) fitting a mathematical relation between the chemical shift of the creatine relative to water and the temperature; and (3) performing CEST imaging on creatine in a sample, and calculating the temperature according to the mathematical relation, fitted in step (2), between the chemical shift of the creatine relative to water and the temperature. In the temperature measuring method, the creatine is taken as an endogenous reference, and highly-spatial-resolution, highly-sensitive, and non-invasive absolute temperature measurement can be implemented by means of temperature dependence of a CEST effect of Cr and water.
    Type: Application
    Filed: January 19, 2022
    Publication date: January 30, 2025
    Applicant: SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGY
    Inventors: Lijuan Zhang, Chao Zou, Siqi Cai, Shihui Zhou, Yang Zhou, Hairong Zheng, Xin Liu
  • Patent number: 12208242
    Abstract: A closed-loop artificial pancreas system based on a wearable monitoring method is provided.
    Type: Grant
    Filed: November 13, 2020
    Date of Patent: January 28, 2025
    Assignee: SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGY CHINESE ACADEMY OF SCIENCES
    Inventors: Zedong Nie, Jingzhen Li, Yuhang Liu
  • Publication number: 20250025497
    Abstract: Use of phosphorus-based material in preparation of medicament for treating tumors. The phosphorus-based material is selected from a material which is convertible to produce phosphate ions in an acidic environment, and the phosphorus-based material can be converted by tumor cells phagocytosis to produce a large number of phosphate ions to change the intraceullar environment and extracellular environment, thereby inhibiting proliferation of tumor cells and inducing death of tumor cells. This process has no significant effect on normal cell activities. By applying the phosphorus-based material to the preparation of a medicament for treating tumor in a manner as mentioned above, the amplification and metastasis of tumor cells can be effectively inhibited, thereby the metastasis of the tumor cells and recurrence of the tumor can be prevented more effectively, improving the therapeutic effect of the tumor. The phosphorus-based material has little effect on normal cells and tissues in the course of treatment.
    Type: Application
    Filed: October 9, 2024
    Publication date: January 23, 2025
    Applicant: SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGY, CHINESE ACADEMY OF SCIENCES
    Inventors: Xuefeng YU, Wenhua ZHOU, Ting PAN, Haodong CUI
  • Patent number: 12190568
    Abstract: Methods and apparatuses for training a magnetic resonance imaging model, electronic devices and computer readable storage media are provided.
    Type: Grant
    Filed: August 16, 2022
    Date of Patent: January 7, 2025
    Assignee: SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGY
    Inventors: Hairong Zheng, Xin Liu, Na Zhang, Zhanli Hu, Qihang Chen, Dong Liang, Yongfeng Yang
  • Patent number: 12180609
    Abstract: Provided are composite array electrode, preparation method thereof and use thereof. The composite array electrode comprises a microelectrode array substrate, and a modification layer formed on a surface of a microelectrode of the microelectrode array substrate, wherein the modification layer comprises a plurality of electrically conductive layers arranged at intervals on the surface of the microelectrode, an insulating layer arranged on the surface of the microelectrode except the electrically conductive layers, and wherein material for the electrically conductive layers comprises one or more of nano platinum, nano iridium, conductive polymer and carbon nanotubes. The composite array electrode effectively eliminates the influence of edge effect such that the electric field distributes uniformly on the microelectrode surface of the composite array electrode, significantly improving electrochemical performance and detection capability of the electrode.
    Type: Grant
    Filed: June 15, 2022
    Date of Patent: December 31, 2024
    Assignee: SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGY
    Inventors: Qi Zeng, Tianzhun Wu
  • Publication number: 20240419897
    Abstract: The present application is suitable for the technical field of data processing, and provides a data error correction method and apparatus and an electronic device. The method includes: decoding a base sequence to be subjected to error correction into a first text, the base sequence to be subjected to error correction being composed of a plurality of bases; performing word segmentation on the first text to obtain a plurality of text units; performing error detection on the plurality of text units to obtain a text unit having an error; and performing error correction on the base sequence to be subjected to error correction according to the text unit having the error. By means of the above method, error correction for data can be achieved, and the storage cost of DNA can also be reduced.
    Type: Application
    Filed: May 24, 2024
    Publication date: December 19, 2024
    Applicant: SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGY CHINESE ACADEMY OF SCIENCES
    Inventors: Junbiao DAI, Mingwei LU, Xiaoluo HUANG
  • Publication number: 20240413708
    Abstract: The present application relates to the technical field of motors, and provides a matrix motor unit structure and a matrix motor. The matrix motor unit comprises at least two motor elements, and the motor elements are connected in an array form in a same plane and defined a motor main body structure. According to the matrix motor unit structure provided by the present application, the motor elements are compactly arranged, and a structure can be shared among the motor elements, so that the overall size and weight can be further reduced, and a higher output torque is obtained.
    Type: Application
    Filed: August 21, 2024
    Publication date: December 12, 2024
    Applicant: SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGY
    Inventor: Tianfu SUN
  • Publication number: 20240398999
    Abstract: The present invention belongs to the field of nanomedicine, and provides a DC biomimetic membrane nanoparticle loaded with an NIR-II AIE dye, a preparation method therefor and use thereof. The DC biomimetic membrane nanoparticle loaded with the NIR-II AIE dye comprises a DC membrane and an NIR-II AIE dye loaded therein, wherein the NIR-II AIE dye has photothermal characteristics. The DC biomimetic membrane nanoparticle loaded with the NIR-II AIE dye provided by the present invention not only solves the problem that the NIR-II AIE dye is poor in water solubility and limited in fluorescence imaging, but also increases the enrichment efficiency of the NIR-II AIE dye coated by the DC membrane at a tumor site and successfully activates the activity of T cells in vivo.
    Type: Application
    Filed: May 31, 2023
    Publication date: December 5, 2024
    Applicants: SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGY CHINESE ACADEMY OF SCIENCES, THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Lintao CAI, Xing YANG, Ping GONG, Pengfei ZHANG, Benzhong TANG, Tsz Kin KWOK, Ting YANG, Qiqi LIU, Xiuwen ZHANG, Xinghua YU, Luo HAI
  • Patent number: 12159706
    Abstract: The present application provides an image-driven brain atlas construction method and apparatus, a device and a storage medium, and involves in the field of medical imaging technologies. The method includes: acquiring a node feature matrix, where the node feature matrix includes time sequences of multiple nodes of a brain; performing hypergraph data structure transformation on the node feature matrix to acquire a first hypergraph incidence matrix; inputting the first hypergraph incidence matrix and the node feature matrix into a trained hypergraph transition matrix generator for processing to output and acquire a first hypergraph transition matrix, where the first hypergraph transition matrix characterizes a constructed multi-modal brain atlas. The technical solution provided by the present application can construct the multi-modal brain atlas, and this multi-modal brain connection structure can express more feature information.
    Type: Grant
    Filed: February 7, 2021
    Date of Patent: December 3, 2024
    Assignee: SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGY
    Inventors: Shuqiang Wang, Junren Pan, Yanyan Shen
  • Patent number: 12154036
    Abstract: The present disclosure relates to an enhanced generative adversarial network and a target sample recognition method. The enhanced generative adversarial network in the present disclosure includes at least one enhanced generator and at least one enhanced discriminator, where the enhanced generator obtains generated data by processing initial data, and provides the generated data to the enhanced discriminator; the enhanced discriminator processes the generated data and feeds back a classification result to the enhanced generator; the enhanced discriminator includes: a convolution layer, a basic capsule layer, a convolution capsule layer, and a classification capsule layer, and the convolution layer, the basic capsule layer, the convolution capsule layer, and the classification capsule layer are sequentially connected to each other.
    Type: Grant
    Filed: August 21, 2020
    Date of Patent: November 26, 2024
    Assignee: SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGY CHINESE ACADEMY OF SCIENCES
    Inventors: Shuqiang Wang, Yanyan Shen, Wenyong Zhang
  • Patent number: 12153175
    Abstract: A method for processing positron emission tomography data is provided, this method includes: obtaining a first coordinate and a second coordinate respectively corresponding to two ends of a response line to be processed; determining corresponding dimensional coordinates of the response line to be processed in a sinogram based on the first coordinate and the second coordinate; and generating the sinogram corresponding to the response line to be processed based on the dimensional coordinates. According to this method, the amount of calculation of system matrix is reduced, the accuracy of position information of the generated response line is improved, and the accuracy of generated sinogram is improved accordingly.
    Type: Grant
    Filed: May 25, 2022
    Date of Patent: November 26, 2024
    Assignee: SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGY CHINESE ACADEMY OF SCIENCES
    Inventors: Zhanli Hu, Yongfeng Yang, Chunhui Zhang, Zhonghua Kuang, Xiaohui Wang, San Wu, Dong Liang, Xin Liu, Hairong Zheng
  • Patent number: 12148122
    Abstract: The present invention provides a panoramic presentation method and apparatus. The present invention presents a panoramic image by using a combined structure of a single fisheye projector and a spherical screen in hardware, employs a geometrical relationship between a fisheye lens and the position of a viewer and isometric projection transformation, and enables 180° fisheye projection to present 720° environment information to the viewer in the center of the spherical screen, greatly simplifying the image conversion process and realizing zero distortion. According to a 720° panorama one-step generation method based on a single virtual camera in software, complex steps of collecting six images by a plurality of cameras, synthesizing a cube map and then converting the cube map into a panorama are not needed, the vertex position of a scene is directly adjusted in the process from a 3D space to a 2D image.
    Type: Grant
    Filed: April 26, 2022
    Date of Patent: November 19, 2024
    Assignee: SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGY CHINESE ACADEMY OF SCIENCES
    Inventors: Qin Yang, Pengfei Wei, Liping Wang
  • Publication number: 20240369583
    Abstract: An Alzheimer's disease biomarker, and a screening method therefor and use thereof. The Alzheimer's disease biomarker is 11(Z), 14(Z)-eicosadienoic acid. The screening method for the Alzheimer's disease biomarker comprises: acquiring samples, testing the samples, and performing structural identification and data analysis on metabolites in the samples, wherein specifically, metabolites in faeces samples can be tested by liquid chromatography-mass spectrometry, to carry out structural identification on the metabolites; and selecting a metabolite showing a difference from the metabolite level of a control group as the Alzheimer's disease biomarker.
    Type: Application
    Filed: September 16, 2021
    Publication date: November 7, 2024
    Applicant: SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGY CHINESE ACADEMY OF SCIENCES
    Inventors: Yu CHEN, Yijing CHEN, Yingying FAN
  • Publication number: 20240368588
    Abstract: A method for high-throughput TAG to TAA conversion on the genome are provided. The method comprises the following steps: co-transfecting a gRNA array pool or a transcription product thereof, a plasmid containing an mCherry-inactivated eGFP reporter molecule and an sgRNA plasmid for editing and activating eGFP in a stable cell of an inducible base editor; or by transfecting an 43-all-in-one expression vector or a transcription product thereof to cells with stable inducible base editor, high-flux TAG to TAA conversion in single cells is realized, and through multiple cyclic operations, almost all TAG to TAA conversion in the whole genome of cells of common model organisms can be realized.
    Type: Application
    Filed: March 29, 2024
    Publication date: November 7, 2024
    Applicants: SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGY, SHENZHEN INSTITUTE OF ADVANCED TECHNOLOGY CHINESE ACADEMY OF SCIENCES
    Inventor: Yuting CHEN
  • Patent number: 12121229
    Abstract: A soft-bodied apparatus and a method for opening an eyelid are provided. The apparatus includes: a head support module, a real-time eyelid positioning module, a robot end-effector real-time positioning module, and an automatic eyelid opening operation module. The automatic eyelid opening operation module includes a robot body and a robot control system. The robot body is provided with a multi-axis rigid body mechanical arm and a soft-bodied end-effector. The robot control system takes the real-time poses of the upper and lower eyelids of the user as a motion target, and takes the real-time shape and the pose of the soft-bodied end-effector as feedback information to control motion of the robot body to automatically open the eyelid.
    Type: Grant
    Filed: February 5, 2021
    Date of Patent: October 22, 2024
    Assignee: SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGY CHINESE ACADEMY OF SCIENCES
    Inventors: Zeyang Xia, Yangzhou Gan, Hao Deng, Jing Xiong
  • Patent number: 12121897
    Abstract: A microfluidic system, including: a container, an ultrasound transmitter assembly, and a phononic crystal plate. The container is configured to accommodate a solution containing microparticles. The ultrasound transmitter assembly is configured to transmit ultrasonic waves to the phononic crystal plate, where the ultrasonic waves have a frequency which is the same as a resonance frequency of the phononic crystal plate. The phononic crystal plate is placed in the solution, and configured to generate a local acoustic field on a surface of the phononic crystal plate under excitation of the ultrasonic waves, and induce an acoustic microstreaming vortex to generate an acoustic streaming shear stress on the microparticles. The phononic crystal plate defines therein cavities, the respective cavities are arranged periodically in the phononic crystal plate, and all the respective cavities are filled with gas.
    Type: Grant
    Filed: December 21, 2018
    Date of Patent: October 22, 2024
    Assignee: SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGY
    Inventors: Hairong Zheng, Fei Li, Feiyan Cai, Long Meng, Yang Xiao, Fei Yan