Abstract: A pre-termination module box and an optical fiber distribution box using same are provided, twelve groups of MDC adapters configured at a front end of a box body and arranged in a horizontal, single row. Each group of the twelve groups of MDC adapters adopts at least one two-core MDC connector, and a plurality of groups of MPO adapters configured at a rear end of the box body and arranged in a horizontal single row to connect with the twelve groups of MDC adapters. A receiving room is formed in the box body for receiving patch cords that are connected between the MDC and MPO adapters, a locking member arranged at the rear end and configured to lock the pre-termination module box in the optical fiber distribution box, which has high wiring capacity and is conducive to reducing a floor area of a central machine room and saving costs.