Abstract: The disclosure provides a non-therapeutic method for regulating DAT gene expression in a cell, which includes the step of increasing or decreasing an amount of a miR-132/212 in the cell; further provides a use of the above miRNA, an enhancer thereof or an attenuator thereof in preparing a drug for regulating uptake of dopamine by a cell; and an application of the above miRNA, the enhancer thereof or the attenuator thereof in preparing a drug for treating psychoactive substance addiction.
Type:
Application
Filed:
January 19, 2021
Publication date:
July 29, 2021
Applicant:
Shenzhen Kangning Hospital (Shenzhen Mental Health Institute, Shenzhen Mental Health Center)
Inventors:
Xiaojian JIA, Han RONG, Mei YANG, Huiming LIU, Tiebang LIU