Patents Assigned to Shenzhen New Industries Biomedical Engineering Co., LTD.
  • Patent number: 11543423
    Abstract: The present disclosure relates to a cuvette box conveying device, a cuvette box conveying method, and a sample analyzer. The cuvette box conveying device includes a frame. The frame includes a new box placing position and a waste box recycling position. The new box placing position and the waste box recycling position are arranged on different layers in the direction of Z axis, so as to reduce the space occupied by the new box placing position and the waste box recycling position on an XY plane. In the cuvette box conveying device, the space occupied by the new box placing position and the waste box recycling position on the XY plane is reduced by arranging the new box placing position and the waste box recycling position on different layers in the direction of Z axis.
    Type: Grant
    Filed: December 11, 2019
    Date of Patent: January 3, 2023
    Assignee: Shenzhen New Industries Biomedical Engineering Co., Ltd.
    Inventors: Liang Zhu, Shiming Feng, Li Yin, Yingzu Chang
  • Patent number: 11513116
    Abstract: The present disclosure relates to a cleaning device and a chemiluminescence detector. A cleaning device is provided with a cup inlet station and a cup outlet station, wherein the cleaning device comprises a pedestal, a plurality of magnetic adsorption components, a turntable arranged on the pedestal, and a primary cleaning mechanism arranged on the pedestal, wherein each of the plurality of magnetic adsorption components comprises a plurality of magnets; magnetic adsorption heights of a plurality of magnets of the first magnetic adsorption component are equal and are recorded as A; magnetic adsorption heights of a plurality of magnets of the middle magnetic adsorption component are equal and are recorded as B, and B>A.
    Type: Grant
    Filed: September 9, 2021
    Date of Patent: November 29, 2022
    Assignee: Shenzhen New Industries Biomedical Engineering Co., Ltd.
    Inventors: Liang Zhu, Li Yin, Yi Hu, Dingping Ban, Wanguan Yi, Shuai Tong
  • Patent number: 11504753
    Abstract: A cleaning module, a sample analyzer with the cleaning module and a cleaning method. Wherein, the cleaning module may include a disk body assembly and a cleaning assembly. The disk body assembly may include a disk body, the cleaning assembly and the disk body may move relatively, and the disk body and the cleaning assembly complete extraction of waste fluid and cleaning on a path of moving relatively.
    Type: Grant
    Filed: April 24, 2020
    Date of Patent: November 22, 2022
    Assignee: Shenzhen New Industries Biomedical Engineering Co., Ltd.
    Inventors: Liang Zhu, Shuai Tong, Wanguan Yi, Li Yin, Yi Hu, Dingping Ban
  • Patent number: 11150257
    Abstract: The present disclosure relates to a sample rack loading system and loading method, and a chemiluminescence detector. The loading system includes: a sample rack storage device, provided with multiple sample holders for storing sample racks; a sample rack transmission device, comprising a rail component and a sample rack block piece mechanism; and a sample rack transfer device, transfers the sample racks between the sample rack storage device and the sample rack transmission device; the sample rack block piece mechanism is configured to block or unblock transmission passages of the rail component; and a guide block is arranged on the sample rack transfer device. When transfer rails of the sample rack transfer device are in abutment with the transmission passages, the guide block drives the sample rack block piece mechanism to unblock the transmission passages.
    Type: Grant
    Filed: September 28, 2018
    Date of Patent: October 19, 2021
    Assignee: Shenzhen New Industries Biomedical Engineering Co., Ltd.
    Inventors: Xiaotao Chen, Li Yin, Liang Zhu, Yixian Wang, Xiongjie Zhang, Gang Zhou
  • Patent number: 11143652
    Abstract: The present disclosure relates to, a magnetic microbeads adsorption mechanism, which is configured to adsorb a magnetic microbeads in a reaction cup and is provided with a cup inlet station and a cup outlet station; the magnetic microbeads adsorption mechanism includes a pedestal, a turntable and multiple magnetic adsorption components; the turntable is rotatably mounted on the pedestal; the turntable can drive the reaction cup to rotate around a central axis of the turntable; the multiple magnetic adsorption components are arranged on a mounting circumference of the pedestal at intervals; the mounting circumference and rotation track of the reaction cup are concentrically arranged; and during a process when the reaction cup rotates from the cup inlet station to the cup outlet station, the adsorption height of the magnetic microbeads relative to cup bottom of the reaction cup can be changed.
    Type: Grant
    Filed: January 21, 2019
    Date of Patent: October 12, 2021
    Assignee: Shenzhen New Industries Biomedical Engineering Co., Ltd.
    Inventors: Liang Zhu, Li Yin, Yi Hu, Dingping Ban, Wanguan Yi, Shuai Tong
  • Patent number: 11085942
    Abstract: The present disclosure provides a consumable box automatic transmission device. The consumable box automatic transmission device includes a consumable box storage mechanism, configured to load and store consumable boxes, and a consumable box lifting mechanism, located above the consumable box storage mechanism; the consumable box lifting mechanism is able to lift the consumable boxes; the consumable box storage mechanism and the consumable box lifting mechanism is able to respectively store and transmit the consumable boxes; the consumable box storage mechanism is able to transmit the consumable boxes to the bottom of the consumable box lifting mechanism; and the consumable box lifting mechanism receives the consumable boxes at a bottom and lifts the consumable boxes to a top layer of the consumable box lifting mechanism. In this way, parallel consumable box transmission can be achieved, and continuous consumable box conveyance is achieved, thereby reducing manual care or frequent manual operation.
    Type: Grant
    Filed: November 2, 2018
    Date of Patent: August 10, 2021
    Assignee: Shenzhen New Industries Biomedical Engineering Co., Ltd.
    Inventors: Liang Zhu, Li Yin, Shiming Feng, Guoyao He, Yi Hu, Dingping Ban, Lina Lin
  • Patent number: 11016029
    Abstract: The present disclosure relates to a measuring chamber, a working method of the measuring chamber, a chemiluminescence measurement method of the measuring chamber and a chemiluminescence detector. The measuring chamber includes a dark chamber, a first substrate nozzle, a photomultiplier detection component, a waste liquor adsorption needle component, a reaction cup turntable and a plurality of reaction cup processing stations; the reaction cup turntable is provided in the measuring chamber rotationally; and the plurality of reaction cup processing stations are sealed in a mutually light-isolated manner. When the instrument works, reaction cups in the reaction cup turntable are moved in the dark chamber; and after the reaction cups are moved to corresponding processing stations for processing the reaction cups, the plurality of different processing stations for processing, the reaction cups may simultaneously process the reaction cups moved to the corresponding reaction cup processing stations.
    Type: Grant
    Filed: September 21, 2018
    Date of Patent: May 25, 2021
    Assignee: Shenzhen New Industries Biomedical Engineering Co., Ltd.
    Inventors: Li Yin, Liang Zhu, Yi Hu, Dingping Ban, Junhui Tang, Jinhong Wu
  • Patent number: 11009517
    Abstract: Some embodiments of the disclosure provide a sample rack scheduling control method. The method includes the following steps: respectively obtaining a state of each position node on each preset delivery path, wherein the state of each position node includes an available state and an occupancy state; and for each of the delivery paths, if a target position node on the delivery path and position nodes between the target position node and a start position node all are in the available state, marking the target position node on the delivery path and the position nodes between the start position node and the target position node all as the occupancy state, and controlling a current sample rack at the start position node to move to the target position node. The present disclosure further provides a sample rack scheduling control system and a medical detection device.
    Type: Grant
    Filed: November 29, 2018
    Date of Patent: May 18, 2021
    Assignee: Shenzhen New Industries Biomedical Engineering Co, Ltd
    Inventors: Junhui Tang, Caiqing Zhong, Xiaotao Chen, Jiang Li, Shujuan Chen, Ying Hu
  • Patent number: 10705079
    Abstract: Disclosed is a method for preparing a magnetic microsphere for the separation of biological proteins. A magnetic microsphere matrix is treated by formulating and using an appropriate emulsified liquid, and modification of the surface of the magnetic microsphere matrix is realized by emulsion polymerization, thereby obtaining a magnetic microsphere coated with a polyacrylate polymer layer. Said emulsified liquid comprises the following components therein: acyclic acid monoester compounds, acyclic acid glycol compounds, initiators and optionally anionic surface active agents and water. The magnetic microsphere significantly reduces the non-specific adsorption of other proteins, without affecting the joining ability for a specific protein, when used in the separation of biological proteins. A new selection is provided to realize the separation engineering of high protein specificity adsorption.
    Type: Grant
    Filed: May 29, 2014
    Date of Patent: July 7, 2020
    Assignee: SHENZHEN NEW INDUSTRIES BIOMEDICAL ENGINEERING CO., LTD.
    Inventors: Wei Rao, Kai Du, Li Zhao
  • Patent number: 10472400
    Abstract: A cardiac troponin I ultra-sensitive detection reagent kit, a preparation method, and a detection method. The reagent kit comprises at least one first anti-cardiac troponin I antibody marked with a trace marker and at least one second anti-cardiac troponin I antibody coated on magnetic microspheres, the first anti-cardiac troponin I antibody and cardiac troponin I binding site being different from the second anti-cardiac troponin I antibody and cardiac troponin I binding site. The reagent kit may further comprise a diluent capable of significantly reducing non-specific binding in a detection process, so as to further increase the detection accuracy and sensitivity. The method using the reagent kit to detect cardiac troponin I sensitively and accurately detects the amount of cardiac troponin I in a sample, and provides more timely and reliable information for the early diagnosis and treatment of AMI.
    Type: Grant
    Filed: February 10, 2015
    Date of Patent: November 12, 2019
    Assignee: SHENZHEN NEW INDUSTRIES BIOMEDICAL ENGINEERING CO., LTD
    Inventors: Wei Rao, Jinyun Yuan, Qin Li, Sheng Wang, Hong Xu, Wu Li, Tinghua Li, Jinqiu Fu
  • Patent number: 10451624
    Abstract: A reagent kit used for detecting lipoprotein-associated phospholipase A2, and a preparation method for the reagent kit. The reagent kit comprises one or a plurality of first anti-lipoprotein-associated phospholipase A2 antibodies used for binding lipoprotein-associated phospholipase A2 to be measured, and one or a plurality of second anti-lipoprotein-associated phospholipase A2 antibodies marked with a trace marker and binding with the lipoprotein-associated phospholipase A2 to be measured at another site, different from the binding site of the lipoprotein-associated phospholipase A2 to be measured and the first anti-lipoprotein-associated phospholipase A2 antibodies. The reagent kit also comprises a displacing agent, so as to further increase the detection accuracy of the reagent kit.
    Type: Grant
    Filed: February 10, 2015
    Date of Patent: October 22, 2019
    Assignee: SHENZHEN NEW INDUSTRIES BIOMEDICAL ENGINEERING CO., LTD
    Inventors: Wei Rao, Jinyun Yuan, Qin Li, Ke Huang, Kai Luo, Dongxia Lin, Tinghua Li
  • Patent number: 10139397
    Abstract: A reaction cuvette moving device and a fully automatic chemiluminescence immunoassay apparatus. The reaction cuvette moving device includes a transmission mechanism and a push mechanism, wherein the transmission mechanism comprises a baseplate and a first horizontal transmission mechanism provided on the baseplate. The push mechanism includes a support assembly, a second horizontal transmission mechanism provided on the support assembly, and a push rod connected to the second horizontal transmission mechanism.
    Type: Grant
    Filed: May 8, 2015
    Date of Patent: November 27, 2018
    Assignee: SHENZHEN NEW INDUSTRIES BIOMEDICAL ENGINEERING CO., LTD.
    Inventors: Wei Rao, Dingping Ban, Wanguan Yi, Liang Zhu, Yi Hu, Xiaotao Chen, Li Yin, Wei Lin
  • Patent number: 10114030
    Abstract: Provided are a detection agent for detecting hydroxy vitamin D, preparation method thereof, and use thereof in 25-hydroxy vitamin D immunological detection. The detection agent comprises a conjugate formed by a 25-hydroxy vitamin D antigen derivative and protein carrier, and magnetic spheres coated by the conjugate. Also provided is a 25-hydroxy vitamin D detection kit comprising the detection agent.
    Type: Grant
    Filed: July 10, 2014
    Date of Patent: October 30, 2018
    Assignee: SHENZHEN NEW INDUSTRIES BIOMEDICAL ENGINEERING CO., LTD
    Inventors: Wei Rao, Tinghua Li, Kai Du, Jinyun Yuan, Kai Luo, Huiling Yu
  • Publication number: 20170305983
    Abstract: A cardiac troponin I ultra-sensitive detection reagent kit, a preparation method, and a detection method. The reagent kit comprises at least one first anti-cardiac troponin I antibody marked with a trace marker and at least one second anti-cardiac troponin I antibody coated on magnetic microspheres, the first anti-cardiac troponin I antibody and cardiac troponin I binding site being different from the second anti-cardiac troponin I antibody and cardiac troponin I binding site. The reagent kit may further comprise a diluent capable of significantly reducing non-specific binding in a detection process, so as to further increase the detection accuracy and sensitivity. The method using the reagent kit to detect cardiac troponin I sensitively and accurately detects the amount of cardiac troponin I in a sample, and provides more timely and reliable information for the early diagnosis and treatment of AMI.
    Type: Application
    Filed: February 10, 2015
    Publication date: October 26, 2017
    Applicant: SHENZHEN NEW INDUSTRIES BIOMEDICAL ENGINEERING CO., LTD
    Inventors: Wei RAO, Jinyun YUAN, Qin LI, Sheng WANG, Hong HU, Wu LI, Tinghua LI, Jinqiu FU
  • Publication number: 20170089890
    Abstract: Disclosed is a method for preparing a magnetic microsphere for the separation of biological proteins. A magnetic microsphere matrix is treated by formulating and using an appropriate emulsified liquid, and modification of the surface of the magnetic microsphere matrix is realized by emulsion polymerization, thereby obtaining a magnetic microsphere coated with a polyacrylate polymer layer. Said emulsified liquid comprises the following components therein: acyclic acid monoester compounds, acyclic acid glycol compounds, initiators and optionally anionic surface active agents and water. The magnetic microsphere significantly reduces the non-specific adsorption of other proteins, without affecting the joining ability for a specific protein, when used in the separation of biological proteins. A new selection is provided to realize the separation engineering of high protein specificity adsorption.
    Type: Application
    Filed: May 29, 2014
    Publication date: March 30, 2017
    Applicant: SHENZHEN NEW INDUSTRIES BIOMEDICAL ENGINEERING CO., LTD.
    Inventors: Wei RAO, Kai DU, Li ZHAO
  • Publication number: 20170067883
    Abstract: Provided are a reaction cuvette loading device and a fully automatic chemiluminescence immunoassay apparatus.
    Type: Application
    Filed: May 8, 2015
    Publication date: March 9, 2017
    Applicant: Shenzhen New Industries Biomedical Engineering Co., LTD.
    Inventors: Wei Rao, Dingping Ban, Wanguan Yi, Liang Zhu, Yi Hu, Xiaotao Chen, Li Yin, Wei Lin
  • Patent number: D868994
    Type: Grant
    Filed: April 27, 2018
    Date of Patent: December 3, 2019
    Assignee: SHENZHEN NEW INDUSTRIES BIOMEDICAL ENGINEERING CO., LTD.
    Inventors: Shiming Feng, Yi Hu, Dingping Ban