Abstract: Provided in the present invention are a magnetic nanosphere coated with modified cardiolipin, and manufacturing method thereof. The magnetic nanosphere coated with modified cardiolipin comprises a modified cardiolipin, a biotin derivative, and a streptavidin magnetic bead. The modified cardiolipin is coupled to the biotin derivative via an —NH—CO structure. The streptavidin magnetic bead is a magnetic nanosphere coupled to streptavidin, and the biotin derivative is coupled to the streptavidin.
Type:
Grant
Filed:
June 30, 2016
Date of Patent:
April 4, 2023
Assignee:
SHENZHEN YHLO BIOTECH CO., LTD.
Inventors:
Fuzhen Xia, Dingbiao Zou, Gang Wang, Xiaoqin Ye, Chungen Qian
Abstract: A device for separating a reagent from a reactor includes a collecting means, provided with a liquid receiving port and a solid receiving port, a holding component disposed above the collecting means and used for placing the reactor, and a rotating mechanism for driving the holding component to rotate. The liquid receiving port and the solid receiving port are arranged at different positions in the circumferential direction of rotation of the holding component, when the holding component passes over the liquid receiving port, reagent in the reactor falls into the liquid receiving port, when the rotating mechanism continues rotating in the original direction until the holding component passes over the solid receiving port, the reactor falls into the solid receiving port from the holding component.
Abstract: Disclosed a chemiluminescence enhancer and a chemiluminescence immunodetection kit. The chemiluminescence enhancer is specifically a betaine and can be used for enhancing the luminance of a luminescent acridine substance. The chemiluminescence immunodetection kit comprising the chemiluminescence enhancer and a luminescent acridine substance features greatly enhanced luminescence signals and high detection sensibility, and can be widely applied to fields such as clinical diagnoses, scientific research, and sanitation analysis.
Type:
Grant
Filed:
July 1, 2016
Date of Patent:
August 18, 2020
Assignee:
SHENZHEN YHLO BIOTECH CO., LTD.
Inventors:
Kunhui Hu, Gang Wang, Fuzhen Xia, Chungen Qian, Liang Zhu, Dingbiao Zou
Abstract: The present invention discloses a zinc transporter 8 antibody chemiluminescence immunoassay kit, including a magnetic microparticle working solution coated with purified zinc transporter 8, a purified zinc transporter 8 working solution labeled with acridinium ester, a zinc transporter 8 antibody calibrator, a chemiluminescent pre-excitation solution and a chemiluminescent excitation solution. In addition, the present invention also discloses a method for preparing the zinc transporter 8 antibody chemiluminescence immunoassay kit.
Type:
Application
Filed:
April 13, 2017
Publication date:
October 24, 2019
Applicant:
SHENZHEN YHLO BIOTECH CO., LTD.
Inventors:
Lin HE, Qiaohong CHEN, Yonghong YANG, Fuzhen XIA, Chungen QIAN, Xing LIU
Abstract: The invention provides a full-automatic erythrocyte sedimentation rate analyzer, which comprises a base as well as a blending device and a detecting device mounted on the base, wherein the blending device comprises a sample rack, a sample rack bracket and a rotating device; the sample rack bracket is arranged on the base, and is connected to the sample rack through a rotating shaft; more than one test tube rack is arranged on the sample rack; the rotating device is connected to the rotating shaft, and drives the rotating shaft to rotationally drive the sample rack to turn over up and down; a plurality of holes are arranged in each test tube rack; a fixing device is arranged in the hole, and used for placing and fixing a closed container containing samples; the detecting device comprises a guide device, a driving device, infrared transmitting and receiving devices having the same quantity as that of the test tube racks, and a mounting rack; the driving device drives the mounting rack to move up and down along
Type:
Grant
Filed:
June 19, 2013
Date of Patent:
August 15, 2017
Assignee:
SHENZHEN YHLO BIOTECH CO., LTD.
Inventors:
Kunhui Hu, Hui Yang, Qingbo Liu, Lin He
Abstract: The present invention provides a method for determining anti-RA33 antibody by ELISA based on a special device. The device comprises a substrate, wherein 8 wells are formed on the substrate, and one end of the substrate is provided with a handle and the handle is adhered with a bar-shaped code with the information of detecting reagent. By using the method and device of present invention, detection reagents can be placed in a single analysis device, thus the operation is simple and it is not easy to go wrong so that the correctness of the detection result is ensured.