Patents Assigned to SHENZHEN ZHONGGE BIOLOGICAL TECHNOLOGY CO., LTD.
  • PYRAZOLO[1,5-a]PYRIDINE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF
    Publication number: 20230219979
    Abstract: Disclosed are a pyrazolo[1,5-a]pyridine compound, a preparation method therefor and a use thereof. Also disclosed is a pharmaceutical composition containing the compound as an active ingredient or a pharmaceutically acceptable salt thereof. The present invention further relates to the use of a compound of formula (I) for treating and preventing diseases that can be treated with wild-type, gene fusion-type and mutant (including but not limited to G804 and G810) RET kinase inhibitors, including diseases or conditions mediated by an RET kinase.
    Type: Application
    Filed: December 11, 2020
    Publication date: July 13, 2023
    Applicant: SHENZHEN ZHONGGE BIOLOGICAL TECHNOLOGY CO., LTD.
    Inventors: Huimin CHENG, Lei FANG, Xiaoming WEN, Zhiqiang LIU, Yu CHEN, Songling MA, Ping CHEN, Zhenzhen QI, Chunyi NIU, Peiyu ZHANG, Lipeng LAI, Jian MA, Shuhao WEN
  • PYRAZOLO[1,5-A]PYRIDINE DERIVATIVE, PREPARATION METHOD THEREFOR, AND COMPOSITION AND USE THEREOF
    Publication number: 20230159523
    Abstract: The present invention relates to a pyrazolo[1,5-a]pyridine derivative, a preparation method therefor, and a composition and a use thereof. Specifically, the present invention relates to the compound of formula (I) and the use thereof for the treatment and/or prevention of wild type, gene-fusion type (including but not limited to KIF5B, CCDC6 and NCOA4) and mutant type (including but not limited to V804, G810 and M918) RET kinases-related diseases, including diseases or conditions mediated by RET kinase.
    Type: Application
    Filed: April 22, 2021
    Publication date: May 25, 2023
    Applicant: SHENZHEN ZHONGGE BIOLOGICAL TECHNOLOGY CO., LTD.
    Inventors: Huimin CHENG, Xiaoming WEN, Zhiqiang LIU, Lei FANG, Yu CHEN, Yong WEI, Guogang ZHANG, Chuansheng LI, Songling MA, Zhenzhen QI, Ping CHEN, Chunyi NIU, Peiyu ZHANG, Lipeng LAI, Jian MA, Shuhao WEN