Abstract: The present disclosure provides a pyrazine compound, a stereoisomer, and a tautomer, and a pharmaceutically acceptable salt thereof in treating a neurodegenerative disease (ND) including Alzheimer's disease, Parkinson's disease, Huntington's disease, frontotemporal dementia (FTD), vascular dementia, HIV-related dementia, multiple sclerosis, progressive lateral sclerosis, Friedreich's ataxia, neuropathic pain, or glaucoma, diabetes mellitus (DM) and a DM-related complication, an inflammation, an oxidative damage, and a mitochondrial disorder-related disease.

Abstract: Provided are bispecific molecules and, in particular, long acting bispecific T cell engagers targeting CD3 and CD47 with improved efficacy, toxic profile and therapeutic window, and methods of making and using such long acting bispecific binding molecules.

Abstract: The present disclosure provides a method of manufacturing an array substrate, the array substrate, and a display device. The method of manufacturing the array substrate includes: a step of preparing a substrate; a step of preparing a driving circuit layer on the substrate; a step of preparing a first passivation layer on the driving circuit layer; a step of preparing an original metal layer on the first passivation layer; a step of preparing an oxygen source layer on the original metal layer; a step of heat-treating the oxygen source layer and the original metal layer, wherein the original metal layer is oxidized to form a second passivation layer.

Abstract: Disclosed are a carbon fiber reinforced ceramic atomizing core and a preparation method thereof. The carbon fiber reinforced ceramic atomizing core includes, by mass, the following raw materials: 30-70 parts of ceramic powder, 1-10 parts of carbon fibers, 10-50 parts of a sintering aid, and 0-30 parts of a pore former. By adding carbon fibers to the carbon fiber reinforced ceramic atomizing core, the atomizing core has columnar pores, which are similar to straight pores formed by fiber stacking of cotton cores, such that the oil conduction capacity and oil retention capacity of the atomizing core are improved, and the atomizing effect and taste of the atomizing core are also improved; and the carbon fibers can be bridged around the pores, thus improving the tenacity and strength of the atomizing core.

Abstract: The present application relates to the technical field of communications, and provides a time synchronization method, an electronic device and a storage medium. A terminal sends a target protocol data unit (PDU) session establishment request to a session management function (SMF) according to a routing policy, wherein the target PDU session establishment request includes a target virtual private link identifier; and the terminal establishes a target PDU session with a target user plane function (UPF). The described method is applied to embodiments of the present application, so that a time synchronization message may be transmitted by means of the target PDU session and an interface indicated by target virtual private link information.

Abstract: A hydraulic damper and an intelligent prosthetics. The hydraulic damper includes a housing, a piston, a piston rod, and a damping adjustment component; an energy storage chamber and a damping chamber loaded with hydraulic fluid are arranged inside the housing; the piston is movably provided in the damping chamber and separates the damping chamber into first chamber and second chamber, the energy storage chamber is closer to the second chamber; the piston rod is inserted into the first chamber, one end of the piston rod is connected to the piston, another end of the piston rod penetrates through one end of the housing away from the energy storage chamber; and the damping adjustment component is connected to the first chamber, the second chamber, and the energy storage chamber, respectively, to adjust resistance of movement of the piston, thereby reducing sealing difficulty and weight of the hydraulic damper.

Abstract: Provided is the use of human serum albumin in the manufacturing of a drug for treating diabetes, obesity, atherosclerosis, Alzheimer's disease, Parkinson's disease and other diseases. In a preferred embodiment, the human serum albumin is the recombinantly prepared young and uninjured human serum albumin, and has achieved excellent effects in reducing the blood sugar level of a diabetic patient.

Abstract: The present disclosure relates to a magnetic circuit assembly of a bone conduction speaker. The magnetic circuit assembly may generate a first magnetic field. The magnetic circuit assembly may include a first magnetic element, and the first magnetic element may generate a second magnetic field. The magnetic circuit may further include a first magnetic guide element and at least one second magnetic element. The at least one second magnetic element may be configured to surround the first magnetic element and a magnetic gap may be configured between the second magnetic element and the first magnetic element. A magnetic field strength of the first magnetic field within the magnetic gap may exceed a magnetic field strength of the second magnetic field within the magnetic gap.

Abstract: A display assembly including a stand, a mounting assembly and a display. The mounting assembly includes a fixed base, a first pivot, a pivotable base, a second pivot, a handle, a plurality of first engagement structures and a second engagement structure. The handle includes a handheld part and a mounting part. The mounting part is connected to the handheld part and pivotally connected to the pivotable base via the second pivot. The first engagement structures are disposed at one of the fixed base and the mounting part of the handle. The second engagement structure is disposed at another one of the fixed base and the mounting part of the handle. The display is fixed on the pivotable base. The first pivot is not coaxial with the second pivot so that the second engagement structure is configured to be engaged with any one of the first engagement structures.

Abstract: Provided are a network slicing method and device, and a storage medium. The method includes: a terminal sending a target protocol data unit (PDU) session establishment request to a local SMF, wherein the PDU session establishment request includes terminal identification information, the PDU session establishment request is forwarded by the local SMF to a local UDM to request a user subscription, the local UDM acquires, according to the terminal identification information, target network slice information corresponding to the terminal identification information and notifies the local SMF, then the local SMF replaces initial network slice information with the target network slice information and determines to establish a PDU session; and the terminal receiving a bearer establishment notification sent by a base station according to an instruction of a local AMF for establishing a radio bearer, wherein the bearer establishment notification is used for instructing the terminal to establish a radio bearer.

Abstract: The present disclosure relates to a dynamic D flip-flop, a register, a chip, and a data processing apparatus. A dynamic D flip-flop is provided, including: an input terminal, configured to receive input data; an output terminal, configured to provide output data in response to the input data; clock signal terminal(s), configured to receive clock signal(s); a first latch unit, configured to latch the input data from the input terminal and transmit the input data under control of the clock signal(s); and a second latch unit, configured to latch data from the first latch unit and transmit the data latched by the first latch unit under control of the clock signal(s), where the first latch unit and the second latch unit are sequentially connected in series between the input terminal and the output terminal, and where the output terminal is configured to use data from the second latch unit as the output data for outputting.

Abstract: The present application discloses an antenna structure and a mobile terminal. In the antenna structure of the present application, a radome corresponding to a region between adjacent antenna elements is made of a metal material, and a radome corresponding to a radiation region of the antenna elements is made of a low dielectric constant material, and a fence-type radome structure is formed. Such a design can ensure the performance of an array antenna in the antenna structure, and can improve the product firmness of the antenna structure.

Abstract: In a method for decoding point cloud media, point cloud media data including a plurality of point cloud samples encapsulated in one or more tracks is received. A compression unit of a point cloud sample in the plurality of point cloud samples is obtained. A media file data box of the point cloud sample includes type information that indicates a type of the compression unit. The type of the compression unit is one of a geometry header indicating a parameter set of geometry information, an attribute header indicating a parameter set of attribute information, a geometry slice indicating point cloud slice data of the geometry information, and an attribute slice indicating point cloud slice data of the attribute information. Whether the compression unit is to be decoded is determined according to the type information. The compression unit is decoded to obtain point cloud data based on the determination.

Abstract: Disclosed are a control method for outputting ultrasound energy, a control host, a system, and a therapy instrument. The control method for outputting the ultrasound energy includes: detecting a moving speed of an ultrasound therapy probe; and controlling a transducer to output the ultrasound energy according to the detected moving speed; when the detected moving speed is less than or equal to a first preset speed value, the transducer is controlled to stop outputting the ultrasound energy.

Abstract: In a method for point cloud prediction processing, an alternative point set of a target point cloud group is obtained from M point cloud groups. The M point cloud groups include the target point cloud group. Coordinate code words of point cloud points in each of the M point cloud groups are identical after shifting by a grouping shift bit number corresponding to the respective point cloud group. Prediction reference points associated with a target point cloud point of the point cloud points in the target point cloud group are obtained from the alternative point set. The target point cloud point is predicted by processing circuitry based on the prediction reference points, to obtain a target predicted attribute value of the target point cloud point.

Abstract: A base assembly includes a mounting structure and a support structure. The mounting structure includes a base body, a main body, and a guide rod provided between the base body and the main body. The support structure includes a sliding element and support legs. The sliding element is slidably connected to the guide rod. Each of the support legs is provided with a rotating end and a support end that are arranged opposite to each other. The rotating end is rotatably connected to the sliding element. The sliding element is slidable toward the main body to drive a plurality of support ends to approach each other, such that the base assembly is in a folded state. One of the base body and the support leg is provided with a first locking element, and the other of the base body and the support leg is provided with a second locking element.

Abstract: A pitch adjustment method and apparatus, and a computer storage medium are provided. the fundamental frequency sequence of the singing sound of the user is obtained, the pitch difference between each candidate melody file and the fundamental frequency sequence at each corresponding time point is calculated, and the sum of all pitch differences of each candidate melody file is calculated. The candidate melody file with the minimum sum is determined as the target melody file, and the pitch of the accompaniment file of the target song is adjusted according to the pitch difference between the target melody file and the original melody file of the target song.

Abstract: In a method for remotely controlling a vehicle, protocol data unit (PDU) session parameter information corresponding to a plurality of remote control modes of the vehicle is obtained by a session management function entity. The plurality of remote control modes includes a first remote control mode and a second remote control mode. While the vehicle is controlled according to the PDU session parameter information corresponding to the first remote control mode, mode switching information is received from an application function entity by the session management function entity. The mode switching information indicates the first remote control mode is to be switched to the second remote control mode. Based on the mode switching information, the vehicle is controlled by the session management function entity to switch to remote control according to the PDU session parameter information corresponding to the second remote control mode.

Abstract: One or more embodiments of the present disclosure relate to a vibration component, including: a mass element and an elastic element. The elastic element may include an enhanced region and a first preprocessing region. The enhanced region may be configured to support the mass element, and the first preprocessing region may provide a first displacement along a vibration direction of the mass element for the mass element.