Patents Assigned to Shering Aktiengesellschaft
  • Patent number: 6894151
    Abstract: The invention relates to crystalline lithium complexes of N-(1-hydroxymethyl-2,3-dihydroxypropyl)-1,4,7-triscarboxymethyl-1,4,7,10 tetraazacyclododecane, their production and the recovery of the salt-free gadolinium complex of N-(1-hydroxymethyl-2,3-dihydroxypropyl)-1,4,7-triscarboxymethyl-1,4,7,10 tetraazacyclododecane from the latter without the use of ion exchangers.
    Type: Grant
    Filed: December 13, 2001
    Date of Patent: May 17, 2005
    Assignee: Shering Aktiengesellschaft
    Inventors: Johannes Platzek, Peter Blaszkiewicz, Orlin Petrov, Holger Hoffmann
  • Patent number: 5843931
    Abstract: Compounds of the general formula I ##STR1## are described, in which x represents an oxygen atom or the hydroxyimino grouping >N.about.OH,R.sup.1 represents a hydrogen atom or a methyl group,G represents a hydrogen atom, a halogen atom or a C.sub.1 -C.sub.4 -alkyl radical, when M and Q are hydrogen atoms or together are an additional bond,Q represents a C.sub.1 -C.sub.4 -alkyl radical when M and G are hydrogen atoms, orG and M together represent a methylene or ethylene group when Q is a hydrogen atom,and R.sup.2, R.sup.3 and R.sup.4 have the meanings given in the description.The novel compounds have pronounced antigestagenic and also antiglucocorticoid, antimineralocorticoid and antiandrogenic properties and are suitable for the preparation of medicaments.
    Type: Grant
    Filed: October 27, 1993
    Date of Patent: December 1, 1998
    Assignee: Shering Aktiengesellschaft
    Inventors: Eckhard Ottow, Wolfgang Schwede, Arwed Cleve, Walter Elger, Krzysztof Chwalisz, Martin Schneider
  • Patent number: 5681543
    Abstract: Polymers comprising a ligand containing a carboxylic acid group, optionally at least one ion of an element of the atomic numbers 21-29, 42, 44 or 57-83 as well as optionally cations of inorganic and/or organic bases, amino acids or amino acid amides are valuable complexing agents and complexes for diagnosis.
    Type: Grant
    Filed: August 10, 1994
    Date of Patent: October 28, 1997
    Assignee: Shering Aktiengesellschaft
    Inventors: Heribert Schmitt-Willich, Julius Deutsch, Heinz Gries, Jurgen Conrad, Reinhard Neumeier
  • Patent number: 5098465
    Abstract: The invention relates to new 2-pyrimidinyl- and 2-triazinylacetic acid derivatives of general formula I ##STR1## in which A, R.sup.2-5 and X have the meanings given in the description, processes for their preparation and their use as herbicides, fungicides and plant growth regulants.
    Type: Grant
    Filed: October 1, 1990
    Date of Patent: March 24, 1992
    Assignee: Shering Aktiengesellschaft
    Inventors: Gabriele Kruger, Christoph Harde, Nikolaus Heinrich, Anita Kruger, Erhard Nordhoff, Gerhard Tarara, Peter Wegner, Clemens Kotter, Gerhard Johann, Richard Rees, Graham P. Jones
  • Patent number: 4600715
    Abstract: .beta.-carboline derivatives of general Formula I ##STR1## wherein R.sup.3 is ##STR2## wherein R.sup.5 is C.sub.1-5 alkyl, R.sup.6 is lower alkyl, aralkyl, or alkoxyalkyl of up to 7 carbon atoms, and R.sup.7 and R.sup.8 are hydrogen C.sub.1-5 alkyl, or, collectively with the amido nitrogen atom, piperidino,R.sup.4 is hydrogen, C.sub.1-3 alkyl, or CH.sub.2 OR.sup.9 wherein R.sup.9 is C.sub.1-3 alkyl, atoms, andR.sup.A is --COOR.sup.10 ##STR3## wherein R.sup.10 is hydrogen, lower alkyl, alkoxyalkyl or alkenyl of up to 5 carbon atoms, or benzyl, or X is oxygen or sulfur, and R.sup.11 and R.sup.12 each are hydrogen, lower alkyl or alkenyl or, collectively with the amido nitrogen atom, represent a hetero ring, are prepared by conventional methods and exhibit, inter alia, an effect on the central nervous system and are suitable for use as psychopharmaceuticals.
    Type: Grant
    Filed: June 22, 1984
    Date of Patent: July 15, 1986
    Assignee: Shering Aktiengesellschaft
    Inventors: Andreas Huth, Ralph Schmiechen, Dieter Seidelmann, Dieter Rahtz, Mogens Engelstoft, Claus T. Braestrup
  • Patent number: 4570007
    Abstract: 2-Amino-1-(1,3-dioxolan-4-yl)ethanol compounds of formula (I) ##STR1## wherein R.sup.1 and R.sup.2 are identical or different and can be hydrogen or a lower alkyl group of 1-4 carbon atoms; or when R.sup.2 is an alkyl group of 1-4 carbon atoms, R.sup.1 can also be an alkoxy group of 1-4 carbon atoms; or R.sup.1 and R.sup.2 combined form an alkylene residue of 5 or 6 carbon atoms,are especially suited as intermediates in the production of opacifying compounds useful in X-ray contrast media.
    Type: Grant
    Filed: April 11, 1985
    Date of Patent: February 11, 1986
    Assignee: Shering Aktiengesellschaft
    Inventors: Ulrich Niedballa, Heinz Gries