Abstract: Disclosed are a series of pyrimidine sulfamide compounds and applications thereof in preparing a drug for a disease related to an ETA receptor antagonist. In particular, disclosed is a derived compound represented by formula (I) or a tautomer or pharmaceutically acceptable composition thereof.
Type:
Grant
Filed:
November 19, 2018
Date of Patent:
May 3, 2022
Assignee:
Shijiazhuang Sagacity New Drug Development Co., Ltd.
Abstract: The present invention relates to a class of tricyclic compounds and an application thereof as a sphingosine 1-phosphate type 1 (S1P1) receptor agonist. The invention specifically relates to a compound represented by formula (II), and a tautomer and pharmaceutically acceptable salt of same.
Type:
Application
Filed:
July 21, 2017
Publication date:
September 30, 2021
Applicant:
Shijiazhuang SagaCity New Drug Development Co., Ltd.
Abstract: The present invention provides a 1,2-dihydro-3H-pyrazolo[3,4-d]pyrimidin-3-one compound having an inhibitory effect on Wee1, and includes an application of the compound in treating various types of tumors.
Type:
Grant
Filed:
January 19, 2018
Date of Patent:
March 23, 2021
Assignee:
SHIJIAZHUANG SAGACITY NEW DRUG DEVELOPMENT CO., LTD.
Abstract: Provided are a PDE4 inhibitor and a use thereof in the preparation of a medicament for treating PDE4 related diseases. Specifically disclosed are the compound as shown in formula (I) and a pharmaceutically acceptable salt thereof.
Type:
Grant
Filed:
August 22, 2017
Date of Patent:
May 26, 2020
Assignee:
SHIJIAZHUANG SAGACITY NEW DRUG DEVELOPMENT CO., LTD.
Abstract: Disclosed is a compound for treating fibrosis-related diseases, and specifically disclosed are the compound represented by formula (I) and a pharmaceutically acceptable salt thereof.
Type:
Grant
Filed:
April 14, 2017
Date of Patent:
March 31, 2020
Assignee:
Shijiazhuang Sagacity New Drug Development Co., Ltd.
Inventors:
Neng-yang Shih, Bin Chen, Lei Zhang, Jian Li, Shuhui Chen