Patents Assigned to Shimadzu Co.
-
Publication number: 20240077463Abstract: Provided is a method capable of shortening the time required for analysis and capable of analyzing various substances produced by microorganisms. A method for analyzing a metabolite of a microorganism according to the present invention includes: a step of supplying a mobile phase including carbon dioxide in a liquid state, a subcritical state, or a supercritical state to a container in which a microorganism cultured in a medium is contained together with the medium, to move a component of a metabolite of the microorganism present in the microorganism and the medium to the mobile phase; a step of introducing a mobile phase to which a component of the metabolite has moved into a column; and a step of performing mass spectrometry on a component of the metabolite contained in the mobile phase that has passed through the column.Type: ApplicationFiled: January 17, 2022Publication date: March 7, 2024Applicants: SHIMADZU CORPORATION, NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY, AJINOMOTO CO., INC.Inventors: Shinnosuke HORIE, Yuka FUJITO, Tomohisa HASUNUMA, Takanobu YOSHIDA, Erika URAHATA
-
Patent number: 10746170Abstract: A preparative separation-purification system has controlling apparatus, which has a pump housing for pumping liquid. The apparatus also has a moving component for reciprocating in the pump housing so as to draw a liquid into the pump housing and discharge the liquid from the pump housing and a driving source for reciprocating the moving component. A setting unit is provided for setting a target liquid supply amount or a target amount which corresponds thereto. A unit amount memory unit is provided for storing a discharge amount of the reciprocating pump per a reciprocal movement of the moving component or a unit amount which is a value corresponding to the discharge amount. A computation unit is provided for computing the smallest multiple number of the unit amount which is equal to or larger than the target amount; and a motor controller for controlling the driving source.Type: GrantFiled: May 13, 2013Date of Patent: August 18, 2020Assignee: Shimadzu Co.Inventor: Tomoyuki Yamazaki
-
Patent number: 10607722Abstract: Provided is a system for helping an operator determine the target ion, collision energy and other analysis conditions. A chromatogram selected by an operator is displayed in a chromatogram display area of an MRM measurement parameter determination window. When the operator selects a point on this chromatogram, the name of a target compound which is registered in an event linked with a range of time including the selected point in time is displayed on a compound name display area. A plurality of mass spectra collected at that point in time are also displayed in a mass spectra display area in a vertically arranged form, using the same scale on the mass axis and the same scale on the intensity axis, with the scales of their mass axes aligned with each other in the vertical direction. The operator can then check whether the selected peak corresponds to the target compound.Type: GrantFiled: April 30, 2013Date of Patent: March 31, 2020Assignee: Shimadzu Co.Inventor: Tomohiro Kawase
-
Patent number: 10434436Abstract: Provided is a gas-blowing vaporizing and drying device, which includes: a sample tube in the form of a double tube including an inner tube for a solution and an outer tube for a gas, the inner tube protruding from one end of the outer tube by length L; and a collection container including a container body and a lid provided with a protrusion sleeve tube, the protrusion sleeve tube including a coupling portion at an end to be located outside the container body and a sleeve portion of a length equal to or longer than L having an open end to be located inside the container body, the coupling portion being designed to be coupled to the aforementioned one end of the outer tube in an air-tight manner.Type: GrantFiled: August 21, 2013Date of Patent: October 8, 2019Assignee: Shimadzu Co.Inventors: Tomoyuki Yamazaki, Przemyslaw Stasica, Bob Boughtflower
-
Patent number: 10393763Abstract: An odor discriminating apparatus includes: a measurement chamber including multiple pieces of odor sensors; a gas introducer for introducing a sample gas into the measurement chamber; concentration adjuster for diluting or condensing the sample gas before introducing the sample gas into the measurement chamber; a vector length computation unit for plotting, in a multidimensional space formed by axes corresponding to detection signals generated by each piece of odor sensors, a measurement point representing a measurement result of the sample gas and for computing a vector length of an odor vector directed from an origin of the multidimensional space to the measurement point; and a controller for feedback-controlling the concentration adjuster so that the vector length computed by the vector length computation unit reaches a predetermined target value.Type: GrantFiled: July 6, 2010Date of Patent: August 27, 2019Assignee: Shimadzu Co.Inventors: Junichi Kita, Motoo Kinoshita, Hisamitsu Akamaru, Masayuki Okada
-
Patent number: 10337988Abstract: Modulation amplitude used for frequency modulation of laser light is set to a1 (<a2) (S1), and laser light is irradiated to a sample state in that state. When moisture concentration is calculated based on secondary harmonic synchronous detection signal that is obtained by synchronous detection of detection signal from transmitted light, the effects of interfering moisture in the optical chamber is ignored, and moisture concentration of the gas to be measured in the sample cell is obtained (S2). If, for example, a high vacuum is created inside the sample cell and the concentration becomes less than the detectable limit (“YES” in S3), the modulation amplitude is switched to a larger amount a2 (S4). By so doing, the detection sensitivity to interfering moisture in atmosphere at atmospheric pressure is increased, and the concentration of interfering moisture is calculated based on the secondary harmonic synchronous detection signal (S5).Type: GrantFiled: June 4, 2012Date of Patent: July 2, 2019Assignee: Shimadzu Co.Inventor: Fumiaki Otera
-
Patent number: 10288561Abstract: A gas analyzer is provided, capable of measuring specific gas amount information within a measurement target gas in which pressure varies greatly. The gas analyzer includes a calculation member for calculating specific gas amount information of the nth cycle, a gas pressure change amount calculation unit for calculating an amount of gas pressure change at each time, and a correction signal creation member for generating a time changing, corrected light intensity at each wavelength ?, by performing a fitting process using the time-changing intensity over a long time period in a time zone in which the amount of gas pressure change is small but using the time-changing intensity over a short time period in a time zone in which the amount of gas pressure change is large.Type: GrantFiled: March 23, 2018Date of Patent: May 14, 2019Assignee: Shimadzu Co.Inventors: Rui Kato, Hideaki Katsu, Fumiaki Otera
-
Patent number: 10062558Abstract: A technique for improving the efficiency of injecting ions into the electrode unit of a funnel structure having high ion-transport efficiency is provided to improve the overall ion-transport efficiency. From an ionization chamber 1 for ionizing a sample under atmospheric pressure, ions are injected through a straight capillary pipe 3 into the inner space of the electrode unit 10 of a funnel structure composed of ring electrodes in a first intermediate vacuum chamber 4. The space for setting the capillary pipe 3 is formed by replacing one or more ring electrodes with C-shaped electrodes whose circumference portion is partially removed. Each C-shaped electrode is arranged so that the ions will be injected perpendicularly to the ion-transport direction.Type: GrantFiled: January 25, 2011Date of Patent: August 28, 2018Assignee: Shimadzu Co.Inventor: Motohide Yasuno
-
Patent number: 10012572Abstract: Provided is a technique for using an optical microscope image of an area on a sample to collect area-specific information characterizing each kind of biological tissue from imaging mass analysis data. On an optical image of a two-dimensional target area on a sample, a difference is examined in the kind of tissue or other features and areas are specified, each regarded as the same kind of tissue. When data processing is initiated, peak information is extracted, for each specified area, from mass spectrum data of all the measurement points. A peak method is applied to each area to extract peak information. Then, when a command to compare a set of areas is given, the peak information of those areas is collected. By comparing the peak information of different areas by a machine learning algorithm or similar judging technique, area-specific peak information is obtained, and this information is stored in memory.Type: GrantFiled: April 27, 2012Date of Patent: July 3, 2018Assignee: Japanese Foundation for Cancer Research, Keio University, National University Corporation Hamamatsu, and Shimadzu Co.Inventors: Masaaki Matsuura, Masaru Ushijima, Masatoshi Wakui, Mitsutoshi Setou, Shigeki Kajihara, Kiyoshi Ogawa
-
Patent number: 4368692Abstract: A wind turbine to convert wind energy into hydraulic energy by a positive displacement hydraulic pump driven by a wind mill. To the oil outlet of the hydraulic pump, a thermo-sensitive control element is attached, which functions when the oil temperature exceeds a certain limit. By the control element, the oil outlet is closed, suppressed, or opened to ensure safety of equipment and for effective use of energy.Type: GrantFiled: August 28, 1980Date of Patent: January 18, 1983Assignee: Shimadzu Co.Inventor: Yasuo Kita