Abstract: In conventional mass spectrometers, if ions are converged by a radio-frequency electric field under the condition of relatively high gas pressure, the ions are decelerated and are delayed, or stagnated in an extreme case, to cause a decrease in the detection sensitivity or an appearance of a ghost peak. By contrast, in the mass spectrometer according to the present invention, lens electrodes 40 comprises four plate-shaped electrodes 41a through 41d, which are radially arranged around the ion optical axis C at intervals of 90 degrees from each other; the four electrodes placed in the plane being approximately perpendicular to the ion optical axis C form a group, and a plurality of the groups are arranged along the ion optical axis C direction at approximately even intervals. The radio-frequency voltages each applied to each of any pair of electrodes adjacent along the direction of the ion optical axis C have a given amount of phase shift.

Abstract: The present invention relates to an optical measuring device which includes container for storing a sample, and an electrode pair for generating an electric field distribution upon impression of a voltage by an electrical power supply, thereby generating or extinguishing diffraction grating formed by a density modulation of particles within the sample. The particles within the sample are evaluated based upon a temporal change of an intensity of a diffracted light beam obtained by irradiating a light beam upon the diffraction grating formed by the density modulation of the particles. The electrodes constituting the electrode pair are configured to have a comb-like electrode teeth that are parallel with each other and are arranged such that the electrode teeth of one electrode are inserted between the electrode teeth of the other electrode. From such configuration, an optical measuring device of a high sensitivity and excellent S/N ratio can be obtained.

Abstract: A turbomolecular pump has multiple stages of alternately arranged rotors and stators. Each of the rotors has blades radially extending from a rotating body. Each of the stators has blades radially extending toward the rotating shaft of the rotating body. The blades provided on at least either of a rotor and a stator are formed in a twisted shape having a blade angle set by an expression in which the radial distance from the rotating shaft is a variable. The expression of the blade angle is composed of a first expression which provides the optimum angle of each blade on the outer side of a predetermined radius of the blade and also composed of a second expression which provides the blade angle suppressing, on the inner side of the predetermined radius, reverse flow of gas molecules.

Abstract: If a scanning rate of a mass scanning is set to be high, the amount of change in an applied voltage between a time of an incidence of a certain ion into a quadrupole mass filter and a time of an emission of the ion therefrom increases. This leads to a change in the condition of a passage of ions, causing the amount of ions to decrease and thereby deteriorating detection sensitivity. In order to avoid this problem, according to the present invention, the values of direct current voltage U and an amplitude V of radio-frequency voltage, both voltages being applied to rod electrodes during a mass scanning, are respectively determined so that a voltage ratio U/V of the voltage U to the amplitude V becomes smaller as the scanning rate becomes higher.

Abstract: In a precessional operation where an X-ray irradiation means and a two-dimensional radiation detector are moving on a circular or elliptic orbit respectively by rotating either one of holding means, that is a C arm or a holding means at angular rate of a·sin(t) under a steady state condition and by rotating the other holding means at angular rate of b·cos(t), the operation is carried out at angular rate (f(t), g(t)) to ensure that the maximum acceleration is smaller than the steady state acceleration during a running-up period until steady is reached.

Abstract: A retainer for use in measuring a force generated between a photocurable resin and a pressing member by a detector includes: a pressing member that has light transmission characteristics and is pressed to the photocurable resin; and a light irradiation block that is provided between the detector and the pressing member and irradiates light emitted from an external light source onto the pressing member in a state of being not contacting a light source and an optical transmission line including an optical fiber.

Abstract: A method of manufacturing radiation tomography apparatus according to this invention includes a first spacer joining step of joining a spacer to a radiation detector, and a second spacer joining step of joining both the radiation detectors to each other via the spacer such that clearance between adjacent scintillators corresponds to integral multiples of an arrangement pitch of scintillation counter crystal. Accordingly, the scintillators provided in the radiation tomography apparatus of this invention are arranged more regularly, which achieves enhanced spatial resolution of the radiation tomography apparatus.

Abstract: A method for differential mobility separation of ions using digital-drive based high voltage fast switching electronics. The digital waveform delivered to the spectrometer is characterized by at least two substantially rectangular pulses of different amplitude and polarity. The control circuitry allows for waveform frequency, duty cycle and pulse amplitudes to be varied independently. Balanced as well as unbalanced asymmetric waveforms can be designed for optimum differential mobility separation of ions. The digital drive is designed for differential mobility spectrometers including parallel plate and segmented plate multipoles of planar symmetry, as well as multipoles of cylindrical symmetry, which may optionally be arranged in series. The use of the digital drive establishes alternating electric fields during which the displacement as a result of ion oscillation is determined by mobility coefficients.

Abstract: A method for fractionating a sample solution includes the steps of setting a first mass spectrometry condition and mass range information; setting a second mass spectrometry condition and mass range information; executing a mass scan by the mass spectrum acquisition portion under the first mass spectrometry condition and obtaining first mass spectrum data; extracting first chromatogram data from the first mass spectrum data based on the first mass range information; executing a mass scan by the mass spectrum acquisition portion under the second mass spectrometry condition to obtain second mass spectrum data; extracting second chromatogram data from the second mass spectrum data based on the second mass range information; switching the first and second spectrometry conditions and repeating the mass scan cyclically; adding the first and second chromatograph data to obtain a chromatogram data; and operating the fraction collector based on the chromatogram data.

Abstract: A method for analyzing a sample in a liquid is provided, which is suitable for easily and reliably preventing a liquid for analysis from being evaporated. When the sample in the liquid is observed by using a scanning probe microscope (SPM), a sealing liquid (17) immiscible with a liquid for analysis (16) is filled around the liquid for analysis (16), in which a sample (13) and a probe (15) are immersed, so as to form a sealing state, in which the liquid for analysis (16) is isolated from an external gas. The SPM enables the probe (15) disposed on a front end of a cantilever (14) to approach a surface of the sample (13) immersed in the liquid, scans the surface of the sample, and detects an interaction between the sample (13) and the probe (15), thereby generating an image.

Abstract: A heater chip (4) as a heat generation element is secured to the surface on the periphery of piping (2). Further, a temperature sensor chip couple (6) is placed on the surface on the periphery of the piping (2), along the direction of flow of fluid flowing in the piping (2). One (6a) of the sensor chips in the couple is placed on the upstream side of the heater chip (4) and the other (6b) is placed on the downstream side of the heater chip (4). The heater chip (4) and the temperature sensor chips (6a, 6b) are formed in a chip type. The temperature sensor chips (6a, 6b) as the pair are placed at positions spaced by the same distance from the heater chip (4).

Abstract: A sample solution containing a sample component is sprayed onto an atmosphere at atmospheric approximately pressure while being applied with electric charge from the tip of a nozzle (1). A sample molecule is released as an ion in a process where charged minute liquid droplets collide with an atmospheric gas and are broken apart, and a solvent is vaporized from the respective liquid droplets. A reflectron (7) in the shape of a half-cut spheroid is arranged in such a manner that a second focal point (F2) is positioned in front of an ion-introducing portion (4) in the spray flow. A discharge electrode (8) is disposed in a position at a first focal point (F1) of the reflectron (7). When pulsed high voltage is applied to the discharge electrode (8), an electric discharge occurs, causing shock waves to be generated. The shock waves reflected on the reflectron (7) are converged on the second focal point (F2).

Abstract: A fluorescence detector is provided to improve the non-linearity of the relationship between concentration and fluorescence intensity when the specimen concentration is high and thereby improve the dynamic range of the measurements. If it is known that the concentration of the specimen to be measured is high, a light beam restriction unit 6 whose aperture 6b in the passage direction of the excitation light Lex is short is used so that only the fluorescence being emitted from a region close to the incident end of the excitation light is condensed by the condensing lens 7 and led to the fluorescence side spectrometer 4 and detected.

Abstract: A vacuum pump configured to exhaust gas includes an inductance gap sensor positioned oppositely near an end face of a rotational axis of a rotational body including a rotor; a plurality of individually formed recesses disposed at the end face facing the gap sensor at respectively different angular positions; and at least one ferromagnetic body disposed in at least one of the recesses. The ferromagnetic body has a Curie temperature approximately equal to an allowable temperature of the rotor. The gap sensor senses inductance changes associated with changes in magnetic permeability of the ferromagnetic body to detect a temperature of the rotor. One of the recesses where the ferromagnetic body is not disposed is a rotational number sensor target. Thus, a rotational number of the rotor is detected based on a change in inductance when the rotational number sensor target passes opposite the inductance sensor.

Abstract: According to the present invention, a matrix reagent prepared by adding methylenediphosphonic acid (MDPNA) having two phosphonic acid groups as an additive to a matrix of 2,5-dihydroxybenzoic acid (DHBA) is used for the preparation of a sample. By using the sample according to the present invention, it is possible to achieve a higher peak intensity of phosphopeptide as compared with a sample in which DHBA is solely used as a matrix without using an additive, or a sample in which phosphoric acid (PA) is used as an additive in addition to DHBA. Further, use of the sample according to the present invention enables the detection of peptides that cannot be detected in a case of the phosphoric acid-added sample.

Abstract: The present invention aims at suppressing noises when a mass analysis is performed by introducing a sample solution into an atmospheric pressure ion source by a pressurized liquid feeding method. As a dilution solvent of the sample solution contained in a sample container, a mixed liquid is used in which the mixture ratio of an organic solvent such as methanol is decreased to 20% and the ratio of water is 80%. Since nitrogen, which is a gas for the pressurization, is soluble in an organic solvent, decreasing the ratio of the organic solvent lowers the saturated dissolution amount and suppresses unstable emergence of the gas in the process of the mass analysis. Consequently, even after the elapse of a considerable length of time from the start of liquid feeding, spike-like noises do not appear in the ion intensity, which stabilizes the ion intensity.

Abstract: A radiation image pickup device comprises temperature control means for maintaining the temperature of an X ray conversion layer to be substantially constant by performing a feedback process for controlling a voltage which is applied to the Peltier element based on the temperature of the X ray conversion layer. The temperature control means starts reading out an electric charge from each pixel (DU), then converts the electric discharge to voltage with a charge amplifier and in a period until an A/D conversion process for the voltage is completed, and restricts a variation in the voltage which is applied to the Peltier element.

Abstract: The analyst previously enters the mass of a fragment that desorbs in the first dissociation with other analysis conditions, as the precursor ion selection reference for the second dissociation through the input unit 25. When the automatic analysis is started, the controller unit 21 sequentially performs the MS1 analysis, MS2 analysis and MS3 analysis. In the course of these analyses, the data processing unit 23 determines the valence of each ion species corresponding to the peaks appearing in the mass spectrum obtained by the MS1 analysis. In addition, after the MS2 analysis, the data processing unit 23 searches for the ion species in conformity with the selection reference in consideration of the determined valence, among the ion species corresponding to the peaks appearing in the mass spectrum by the MS2 analysis. The selected ion is determined as the precursor ion for the second dissociation in the MS3 analysis.

Abstract: A classification apparatus for classifying and separating particles having particle sizes within a predetermined range is disclosed. In a preferred embodiment of the classification apparatus, a center electrode (3) and an outside electrode (4) generate an electric field for classifying charged fine particles according to electric mobility. In the upper part of a housing (1), a sheath gas supply portion (7) is provided. An aerosol supply portion (11) has an introduction port (11a) provided on the outside electrode (4) side in a classification region (5), and supplies a charged aerosol at a constant flow rate through the introduction port (11a). On the downstream side in the flow of a sheath gas in the classification region (5), a larger-size particle discharge portion (13) is provided.

Abstract: A low-frequency high AC voltage from an excitation voltage power source (14) is applied between one electrode (8) and two other electrodes (9A and 9B) to generate a low-frequency AC-excited dielectric barrier discharge within a gas passage (3), thereby creating atmospheric pressure non-equilibrium micro-plasma. A sample gas is mixed with hydrogen inside the passage of a nozzle (51), and further mixed with air outside an exit port (53) to burn, forming a hydrogen flame (57). Then, the sample gas reaches an ionization area (56), where the sample components are ionized due to the effect of light emitted from the plasma. Meanwhile, water molecules generated in the hydrogen flame (57) are supplied into the ionization area (56), whereby some of the sample-molecule ions are hydrated while the others undergo a reaction to form a hydroxonium ion.