Abstract: A moving mechanism and a spray mechanism are controlled to spray a reagent from a nozzle to a sample plate while relatively moving the sample plate and the nozzle. The reagent is applied to an entire application area by moving a spray spot of the reagent sprayed from the nozzle, on the sample plate from a start point to an end point. At this time, the spray spot is moved in a sample placement area after a spray amount of the reagent from the nozzle and a moving speed of the spray spot become constant.

Abstract: In order to appropriately set MSm analysis conditions, an MSm-1 analysis executer (51) makes a mass spectrometer (20) perform an MSm-1 analysis (where m is an integer from 2 to n) to acquire three-dimensional data showing an intensity for each of the N m/z values and each of the M retention times (where N and M are natural numbers). Based on the three-dimensional data, a data matrix creator (41) creates data matrix X in which intensity data are arranged in N rows which differ from each other in m/z value and M columns which differ from each other in retention-time value. A matrix factorization executer (42) determines an N×K spectrum matrix S and K×M profile matrix P (where K is a natural number) by matrix factorization based on data matrix X so that this matrix X is approximated by product SP of the matrices S and P. An m/z detector (43) detects m/z of a precursor ion originating from a sample component from the values of the matrix elements in each column of matrix S.

Abstract: In a mass spectrometer including ion optical elements for transporting ions or controlling their behavior by electric fields, a device state determiner (41, 52) determines whether or not the mass spectrometer is in a normal state based on an ion intensity signal acquired by analyzing a predetermined sample. If the mass spectrometer is in an abnormal state, a charge-up determiner (42, 53) determines whether or not charge-up is present in the ion optical elements based on a change in ion intensity signal in an analysis on the predetermined sample observed when the voltages applied to the ion optical elements are changed according to a predetermined sequence. If charge-up is present, the charge-up determiner determines which ion optical element is likely to have the charge-up. A notifier (8, 61) notifies a user of the results of the determination by the device state determiner and the charge-up determiner.

Abstract: In a mass spectrometer employing laser ionization to ionize a sample, a known sample is irradiated with laser light multiple times, and multiple sets of profile data are acquired each of which is a spectrum showing the relationship between the m/z values and intensities of ions generated from the known sample by one laser irradiation (Step S11). Those sets of profile data are sorted into groups so that one or more sets of profile data are included in each group (Step S12). For each group, a peak list is created which describes the m/z value and intensity of each peak originating from the known sample based on the one or more sets of profile data included in the group (Step S13). A discriminant model for discriminating an unknown sample is created using the peak lists of the plurality of groups and information concerning the kind of the known sample as training data.

Abstract: A pump unit for a chromatograph includes a plunger pump and an upstream check valve. The plunger pump has a pump head and pumps a mobile phase. The upstream check valve is provided upstream of the pump head. The upstream check valve includes a flow-path portion and a temperature regulator. The flow-path portion guides the mobile phase to the plunger pump. The temperature regulator regulates a temperature of the mobile phase passing through the flow-path portion.

Abstract: First and second flow-path portions are opposite to each other, and communicate with each other such that a direction in which an eluent flows through the first flow-path portion and a direction in which an eluent flows through the second flow-path portion are opposite to each other. First and second electrode liquid flow paths are respectively opposite to the first and second flow-path portions. First and second electrode liquids are respectively supplied to the first and second electrode liquid flow paths, such that a direction in which the first electrode liquid flows through the first electrode liquid flow path is same as a direction in which an eluent flows through the first flow-path portion and a direction in which the second electrode liquid flows through the second electrode liquid flow path is same as a direction in which an eluent flows through the second flow-path portion.

Abstract: The method for examining a clinched portion of a tubular body includes the steps of: giving an elastic vibration to a clinched body 90 formed by clinching a tubular body 91 with a clinch-target member 92; and acquiring, for each of a plurality of view areas 95 which differ from each other in the position in the circumferential direction of the tubular body 91, a vibration distribution optically and simultaneously measured within the view area 95 including a clinched portion 93 of the tubular body 91 and the clinch-target member 92, to determine whether or not the state of clinching is satisfactory over the entire clinched portion 93.

Abstract: A driving part of an analysis device includes a cylindrical part on one surface of which a moving mirror is fixed, and a VCM connected at another surface of the cylindrical part and reciprocating the cylindrical part. The VCM includes: a yoke in a cylindrical shape; magnets provided at two ends of the yoke; a fixing part which is in a cylindrical shape enclosing the yoke and fixes, at a bottom surface, the yoke provided with the magnets; a lid part provided with windows and covering an opening surface of the fixing part; a moving part which is arranged between the yoke and the fixing part and on which a coil in a cylindrical shape is fixed; and support parts each including one end fixed to the moving part and another end connected at the another surface of the cylindrical part through the window.

Abstract: An imaging analysis device according to the present invention includes: an analysis execution unit (1) configured to perform analysis by a predetermined analysis method for each of a plurality of measurement points set in a measurement area on a sample and collect imaging data; a reference image acquiring unit (2) configured to acquire a reference image for the measurement area; a regression analysis executer (36) configured to, with respect to the imaging data and the reference image obtained for the same sample, perform predetermined regression analysis calculation with the imaging data as an explanatory variable and data constituting the reference image as a target variable and acquire a regression model; and a predicted image creator (37) configured to apply, to the regression model, imaging data obtained by the analysis execution unit using a sample different from the sample used in the regression analysis executer, and create a predicted image based on a pseudo regression analysis result.

Abstract: A separation channel on which a liquid delivery pump, a separation column, and a detector are provided, the liquid delivering pump being for feeding a mobile phase, the separation column being for separating a component in a sample, and the detector being for detecting peaks of components separated from each other by the separation column, a plurality of liquid handlers each including an injecting part and a collecting part, wherein when one of the plurality of liquid handlers is introduced into the separation channel, the injecting part of the one of the plurality of liquid handlers functions as an injector that executes injection operation of a sample into a mobile phase flowing through the analysis channel upstream of the separation column in the analysis channel and the collecting part of the one the plurality of liquid handlers functions as a fraction collector that executes collection operation of peaks of components separated from each other in the separation column, a selector for selectively switchin

Abstract: A displacement measurement device 10 is provided with: a laser light source 11 for emitting laser light to a measurement area R of a measurement target object S; a focusing optical system (the beam splitter 151, the first reflecting mirror 1521, the condenser lens 155) having a front focal point in the measurement area R and a rear focal point on a predetermined imaging surface (the detection surface 1561); a non-focusing optical system (the beam splitter 151, the diffuser 153, the second reflecting mirror 1522, and the condenser lens 155) in which light from a measurement area R of a correspondence point in the measurement area corresponding to each point of the imaging surface with respect to the focusing optical system is incident on the point of the imaging surface; and a photodetector (image sensor 156) configured to detect light intensity on the imaging surface for each point.

Abstract: Provided is a chromatography system including a usage information storage device, a column usage information holding part, and a usage information managing part. The usage information storage device is provided corresponding to the analytical column incorporated in the chromatography system and is configured to keep usage information for each corresponding analytical column. The column usage information holding part is provided separately from the analytical column and is configured to keep usage information for each of the analytical columns which may be incorporated in the chromatography system. The usage information managing part is configured to update, at a timing when an analysis process of separating a sample injected into the analysis channel using the analytical column is executed, the usage information kept by the usage information storage device and the usage information kept by the column usage information holding part in association with the analytical column to latest usage information.

Abstract: A light source emits excitation light to discharge gas that flows through a dielectric tube. A ground electrode unit includes a first ground electrode and a second ground electrode arranged at a distance from each other in an axial direction of the dielectric tube. A high-voltage electrode is provided between the first ground electrode and the second ground electrode. A first distance between the first ground electrode and the high-voltage electrode is shorter than a second distance between the second ground electrode and the high-voltage electrode. A cover is provided on an outer wall of the dielectric tube at a position between the first ground electrode and the high-voltage electrode. The light source is arranged to emit excitation light such that an optical axis thereof is directed toward a position where the cover is not provided on the outer wall of the dielectric tube.

Abstract: A phase image is formed by calculation from a hologram image of a cell, and segmentation is performed for each pixel for the phase image using a fully convolution neural network to identify an undifferentiated cell region, a deviated cell region, a foreign substance region, and the like. When learning, when a learning image included in a mini-batch is read, the image is randomly inverted vertically or horizontally and then is rotated by a random angle. A part that has been lost within the frame by the pre-rotation image is compensated for by a mirror-image inversion with an edge of a post-rotation image as an axis thereof. Learning of a fully convolution neural network is performed using the generated learning image. The same processing is repeated for all mini-batches, and the learning is repeated by a predetermined number of times while shuffling the training data allocated to the mini-batch. The precision of the learning model is thus improved.

Abstract: This X-ray imaging apparatus includes an X-ray source, an X-ray detector, an arm, an arm driving mechanism, an X-ray detector moving mechanism, a bed, and a control unit. The control unit performs control of a position adjustment operation for adjusting a position of the X-ray detector such that a distance from a surface of a subject model serving as a model of a surface shape of the subject to the X-ray detector becomes a predetermined distance by moving the X-ray detector toward or away from the surface of the subject model.

Abstract: A liquid delivery pump includes a primary plunger pump, a secondary plunger pump fluidly connected in series downstream of the primary plunger pump, and a pressure sensor that detects a system pressure. The liquid delivery pump further includes a liquid delivery control part configured to execute first constant pressure control in a first constant pressure control term and to execute second constant pressure control in a second constant pressure control term. The first constant pressure control term is a term, which is in a liquid delivery cycle consisting of the primary discharge process and the secondary discharge process, in which the primary discharge process is executed, the second constant pressure control term is a part of a term in which the secondary discharge process is executed, and the second constant pressure control term is including a term that is continuous after the first constant pressure control term.

Abstract: For a low-cost, high-accuracy tuning of the voltages applied to electrodes in a mass spectrometer, a chromatograph mass spectrometer (1) includes: a medium supplier (11) which supplies a medium as a mobile phase or carrier gas; a passage (15) which introduces, into the mass spectrometer, the medium supplied from the medium supplier; an ionizer (211) which ionizes the medium together with a substance coming from a member forming the passage into the medium; a measurement executer (25, 26, 43) which performs a mass separation and a measurement of a specific ion, using multiple measurement conditions which differ from each other in the value of voltage applied to at least one electrode included in one or more electrodes in the mass spectrometer; and a voltage value determiner (44) which determines the value of voltage applied to each electrode so that the intensity of the ion satisfies a predetermined criterion.

Abstract: Provided is a mass spectrometer including a vacuum chamber containing a cell used for causing ions originating from a sample to come in contact with a predetermined gas supplied from a gas supplier (20), which includes a three-way valve (204) configured to selectively send the gas into either a first passage (22) for sending the predetermined gas to the cell or a second passage (23) for discharging the gas into vacuum state. The mass spectrometer also includes a controller configured to control the three-way valve so as to send the gas into the second passage during an analysis period in which ions are not caused to come in contact with the gas within the cell and/or during a non-analyzing period, as well as to send the gas into the first passage during an analysis period in which ions are caused to come in contact with the gas within the cell.

Abstract: An ICP-MS includes a control device, a collision cell and a first electrode that are provided on an optical axis of plasma, and a second electrode, a mass separation device, and a detector that are provided on a detection axis. The control device sets, as an axis-shifting voltage to be applied to each electrode of the first electrode and the second electrode in a gas-present mode, the voltage obtained by adding an offset determined according to a mass-to-charge ratio of a target ion to an initial voltage in a gasless mode.