Abstract: Provided is a diagnostic drug for evaluating permeability of intestinal mucosa, including chitin and/or chitosan as a main component. The chitin and/or chitosan to be used preferably has a weight average molecular weight prepared to a range of from 1,000 to 11,600.

Abstract: A headlight (1) for a healthcare worker includes: a base part (10), which has a U-shape, is configured to come into abutment, at a center part of the base part (10), with a back side of a head and neck part of a wearer, and includes a right end part (11) and a left end part (11), each of which is configured to be hung on an upper part of an ear so that the base part (10) is retained on a head; a light source device (20), which extends from both or any one of a vicinity of the end parts (11), includes LEDs as light sources, and is configured to illuminate a region in front of the head; and a controller (30) configured to control an illumination state of the light source device (20). The controller (30) is configured to light the light source device (20) when the base part (10) reaches a predetermined depression angle with a standing state of the wearer serving as a reference.

Abstract: A scintillator includes a support substrate, an emission layer formed on the substrate, made of ZnO with impurities added to have an electron concentration of 2×1019 cm?3 or more and 2×1020 cm?3 or less, and for generating scintillation light in response to incidence of radiation, a protective layer formed on the emission layer and made of a material having a band gap wider than that of ZnO, and a metal layer formed on the protective layer. The support substrate is made of a material transmitting the scintillation light generated in the emission layer. Further, the metal layer functions as a reflection layer for reflecting the scintillation light from the emission layer.

Abstract: A bidirectional DC-DC converter includes a series circuit of a first winding of a first reactor, a second reactor, and a first switch connected to both ends of a first DC power source, a series circuit of a second switch and a second DC power source connected to both ends of the first switch, a series circuit of a second winding of the first reactor, a third reactor, a first selector switch, and a first diode connected to both ends of a series circuit of the second reactor and the first switch, a series circuit of a second selector switch, a second diode, and the second DC power source connected to both ends of a series circuit of the first selector switch and first diode, and a controller turning on/off the switches and the selector switches.

Abstract: A DC-DC converter includes a coupling transformer that has windings 11 and 12, switches (Tr1, Tr2) that are connected through the windings to both ends of a DC power source Vi, a series circuit that is connected to both ends of each of the switches and includes a diode and a smoothing capacitor, and a controller 100 that alternately turns on the switches Tr1 and Tr2 and simultaneously turns on the switches Tr1 and Tr2 for a predetermined overlapping period on every half cycle. The coupling transformer 1 includes an I-shaped core 4, two E-shaped cores 2 and 3 holding the I-shaped core 4 between them, and a gap 5 formed between each of center legs 2a and 3a of the E-shaped cores 2 and 3 and the I-shaped core 4. The windings 11 and 12 are wound around the I-shaped core 4.

Abstract: Provided is a fluorescent labeling material, including zinc oxide nanoparticles each surface-modified with an organic compound having an amino group placed at an outer end thereof. Also provided is a fluorescent labeling agent to be used in vivo or in vitro, including the fluorescent labeling material, in which: EDC or the like is bound thereto through the amino group; and a substance capable of selectively binding to a target to be fluorescently labeled, such as an antibody, is linked thereto.

Abstract: A bidirectional DC-DC converter includes a series circuit of a first winding of a first reactor, a second reactor, and a first switch connected to both ends of a first DC power source, a series circuit of a second switch and a second DC power source connected to both ends of the first switch, a series circuit of a second winding of the first reactor, a third reactor, a first selector switch, and a first diode connected to both ends of a series circuit of the second reactor and the first switch, a series circuit of a second selector switch, a second diode, and the second DC power source connected to both ends of a series circuit of the first selector switch and first diode, and a controller turning on/off the switches and the selector switches.

Abstract: The present invention provides compositions and methods for use in enzyme replacement therapy. The inventors disclose a method of producing membrane bound enzymes in an active soluble form by eliminating the glycosylphosphatidylinositol (GPI) membrane anchor. In particular the inventors disclose a soluble active form of the membrane bound enzyme TNSALP which they produced by deleting the GPI anchor single peptide sequence. They have further shown that this composition is useful for treatment of hypophosphatasia. The inventors also disclose oligo acid amino acid variants thereof which specifically target bone tissue.

Abstract: A modulating light having a wavelength of 600 nm to 1000 nm excluding a range of 870 nm to 910 nm is irradiated to a portion around hair roots such that a light absorptive component existing in a human body around the hair roots absorbs the light for modulating hair growth. The light having the wavelength in the above range enhances hair growth free from causing inflammation, yet safely and gentle to skin.

Abstract: The present invention includes: a main switch Tr1 connected to two ends of a DC power supply Vi via a first primary winding 1a and a second primary winding 1b, connected to the first primary winding in series, of a transformer T1; a series circuit connected to the two ends of the main switch, and including a reactor L1, a diode D1, a smoothing capacitor Co and a hoist winding 1c connected to the second primary winding in series; a series circuit connected to the two ends of the main switch, and including a diode D2, a diode D3 and the smoothing capacitor; a control circuit 10 to turn on and off the main switch; a soft-switching circuit Da1, Tra1, La1, Ca1 to cause the main switch to perform a soft-switching operation each time the main switch turns on; and a switching control circuit 20 to switch the soft-switching circuit between operating and non-operating modes in accordance with the state of a load.

Abstract: A modulating light having a wavelength of 400 nm to 600 nm is irradiated to a portion around hair roots at an energy of 0.01 J/cm2 to 1 J/cm2 over a time period of not more than 1 ms as a flash light such that a light absorptive component existing in a human body around the hair roots absorbs the light for modulating hair growth without causing substantial adverse effect.

Abstract: In order to achieve an object to reduce a surge voltage and suppress noise generation, the present invention provides a DC-DC converter with a snubber circuit, which boosts a voltage Vi of a DC power supply. The snubber circuit includes: a series circuit connected to both ends of a smoothing capacitor Co and including a snubber capacitor Cs and a snubber resistor Rs; a snubber diode Ds1 connected to a node at which the snubber capacitor Cs and the snubber resistor Rs are connected, and to a node at which a reactor Lr1 and an additional winding 1b of a transformer T1 are connected; and a snubber diode Ds2 connected to the node at which the snubber capacitor Cs and the snubber resistor Rs are connected, and to a node at which a reactor Lr2 and an additional winding 2b of a transformer T2 are connected.

Abstract: A resonant power conversion apparatus includes a transformer T1 having a primary winding n1, a secondary winding n2, a tertiary winding n3, and a reset winding nR, a series circuit of switches S1 and S2, a capacitor Cr1 and diode D1 to the switch S1, a capacitor Cr2 and diode D2 to the switch S2, a series circuit of the winding n1 and a diode Dn1, a series circuit of the winding nR and a diode DR, a reactor Lr connected between a connection point of the switches S1 and S2 and a connection point of the windings n2 and n3, a switch S10 connected between the DC power source and the winding n2, a switch S20 connected between the DC power source and the winding n3, and a controller 10 configured to perform a zero-voltage switching operation of the switches S1 and S2.

Abstract: A device 1a for bonding adherends T1 and T2, as a device for bonding biological tissue to biological tissue or a biological tissue bonding material, comprises: a clamping part 2a for clamping the adherends T1 and T2 between members 21a and 22a; a pressing part 3a for pressing the member 22a towards the member 21a; a pressure control part 4a for controlling the pressure by the pressing part 3a; a heating element 5a built into the member 21a; a heating control part 6a for controlling the heating by the heating element 5a; a vibration generating part 7a for generating microvibration; and a vibration control part 8a for controlling the microvibration generated by the vibration generating part 7a.

Abstract: The present invention provides a DC-DC converter including a first series circuit connected to both ends of a first switch and formed of a winding of a first transformer, a first reactor, a first diode, and a smoothing capacitor, a second diode connected to a connection point of a primary winding of the first transformer, the winding of the first transformer and the first switch, and to one end of the smoothing capacitor, a second series circuit connected to both ends of a second switch and formed of a winding of a second transformer, a second reactor, a third diode, and the smoothing capacitor, a fourth diode connected to a connection point of a primary winding of the second transformer, the winding of the second transformer and the second switch, and to the one end of the smoothing capacitor, a third reactor connected to both ends of a series circuit of a secondary winding of the first transformer and a secondary winding of the second transformer, and a control circuit which alternately turns on the first s

Abstract: The present invention includes: a main switch Tr1 connected to two ends of a DC power supply Vi via a first primary winding 1a and a second primary winding 1b, connected to the first primary winding in series, of a transformer T1; a series circuit connected to the two ends of the main switch, and including a reactor L1, a diode D1, a smoothing capacitor Co and a hoist winding 1c connected to the second primary winding in series; a series circuit connected to the two ends of the main switch, and including a diode D2, a diode D3 and the smoothing capacitor; a control circuit 10 to turn on and off the main switch; a soft-switching circuit Da1, Tra1, La1, Ca1 to cause the main switch to perform a soft-switching operation each time the main switch turns on; and a switching control circuit 20 to switch the soft-switching circuit between operating and non-operating modes in accordance with the state of a load.

Abstract: In order to achieve an object to reduce a surge voltage and suppress noise generation, the present invention provides a DC-DC converter with a snubber circuit, which boosts a voltage Vi of a DC power supply. The snubber circuit includes: a series circuit connected to both ends of a smoothing capacitor Co and including a snubber capacitor Cs and a snubber resistor Rs; a snubber diode Ds1 connected to a node at which the snubber capacitor Cs and the snubber resistor Rs are connected, and to a node at which a reactor Lr1 and an additional winding 1b of a transformer T1 are connected; and a snubber diode Ds2 connected to the node at which the snubber capacitor Cs and the snubber resistor Rs are connected, and to a node at which a reactor Lr2 and an additional winding 2b of a transformer T2 are connected.

Abstract: A current-mode controlled DC-DC converter includes a comparator comparing a first or second current detection signal with a first or second reference current that is based on an error voltage of a voltage detection signal, a pulse generator generating a first pulse signal whose ON time is longer than an interval between when the second current detection signal reaches a minimum value and when the second current detection signal reaches the second reference current, a pulse generator generating a second pulse signal whose ON time is longer than an interval between when the first current detection signal reaches a minimum value and when the first current detection signal reaches the first reference current, the second pulse signal being behind the first pulse signal by a half period, and a PWM circuit generating a first or second PWM signal according to the pulse signal and an output signal from the comparator, thereby turning on/off a switch.

Abstract: A resonant power conversion apparatus includes a transformer T1 having a primary winding n1, a secondary winding n2, a tertiary winding n3, and a reset winding nR, a series circuit of switches S1 and S2, a capacitor Cr1 and diode D1 to the switch S1, a capacitor Cr2 and diode D2 to the switch S2, a series circuit of the winding n1 and a diode Dn1, a series circuit of the winding nR and a diode DR, a reactor Lr connected between a connection point of the switches S1 and S2 and a connection point of the windings n2 and n3, a switch S10 connected between the DC power source and the winding n2, a switch S20 connected between the DC power source and the winding n3, and a controller 10 configured to perform a zero-voltage switching operation of the switches S1 and S2.

Abstract: In a synthetic method for porous silica crystals through a hydrothermal reaction, a method for synthesizing porous silica crystals with a size of 0.5 mm or larger in high reproducibility and efficiency is provided using a method for manufacturing the porous silica crystals, wherein a high concentration area with silicon is formed as a partial area inside a hydrothermal synthesis vessel, and at least a part of a surface-smoothed bulk material is present in the high concentration area with silicon to perform the hydrothermal reaction, the bulk material comprising a compound containing both silicon and oxygen as a supply source for a part or a whole of the structure composition elements of the porous silica crystals.