Patents Assigned to Shine-On Biomedical Co., Ltd.
  • Immunomodulation and anti-tumor-related nanobody and nucleic acid encoding sequence thereof, and uses of the same
    Patent number: 11795227
    Abstract: The present disclosure provides an immunomodulation and anti-tumor-related nanobody that specifically binds to a human leukocyte antigen-G, a programmed cell death ligand 1, and CD3 ?. The present disclosure also provides the nucleic acid sequence of the immunomodulation and anti-tumor-related nanobody, and use of the immunomodulation and anti-tumor-related nanobody for treating cancer and immune-related disorders.
    Type: Grant
    Filed: March 21, 2022
    Date of Patent: October 24, 2023
    Assignee: SHINE-ON BIOMEDICAL CO., LTD.
    Inventors: Der-Yang Cho, Shao-Chih Chiu, Shi-Wei Huang, Chih-Ming Pan, Mei-Chih Chen, Yu-Chuan Lin, Yeh Chen
  • PRODUCTION OF EXOSOMES AND USES THEREOF
    Publication number: 20230211009
    Abstract: A method for producing exosomes in a large-scale by using a cyclic tensile bioreactor to stimulate cells to release exosomes. In addition, the exosome having an anti-HLA-G protein specific for cancer is used as a delivery vehicle to deliver therapeutic agents for treating cancer.
    Type: Application
    Filed: December 2, 2022
    Publication date: July 6, 2023
    Applicants: CHINA MEDICAL UNIVERSITY, China Medical University Hospital, Shine-On Biomedical Co., Ltd.
    Inventors: Yi-Wen Chen, Der-Yang Cho, Hsin-Yuan Fang, Ming-You Shie, Chih-Ming Pan, Kai-Wen Kan, Cheng-Yu Chen, Min-Hua Yu, Shao-Chih Chiu