Patents Assigned to Shire ViroPharma Incorporated
  • Maribavir isomers, compositions, methods of making and methods of using
    Patent number: 10765692
    Abstract: The invention relates to novel compositions and methods of using maribavir which enhance its effectiveness in medical therapy, as well as to maribavir isomers and methods of use thereof for counteracting the potentially adverse effects of maribavir isomerization in vivo in the event it occurs.
    Type: Grant
    Filed: October 25, 2019
    Date of Patent: September 8, 2020
    Assignee: Shire Viropharma Incorporated
    Inventor: John D. Peabody, III
  • Pharmaceutical compositions for glucocorticoid replacement therapy
    Patent number: 10583146
    Abstract: The invention relates to glucocorticoid replacement therapy and provides pharmaceutical compositions and kits designed to deliver one or more glucocorticoids to a subject in need thereon in a manner that results in serum levels of the glucocorticoid that essentially mimic that of a healthy subject for a clinically relevant period of time. The pharmaceutical compositions and kits are prepared in such a way that a first part of one or more glucocorticoids is substantially immediately released and a second part of one or more glucocorticoids is released over an extended period of time of at least about 8 hours. The invention also relates to a method for treating diseases requiring glucocorticoid treatment such as in subjects having a glucocorticoid deficiency disorder.
    Type: Grant
    Filed: April 17, 2014
    Date of Patent: March 10, 2020
    Assignee: SHIRE VIROPHARMA INCORPORATED
    Inventors: Stanko Skrtic, Jörgen Johnsson, Hans Lennernäs, Thomas Hedner, Gudmundur Johannsson
  • Maribavir isomers, compositions, methods of making and methods of using
    Patent number: 10485813
    Abstract: The invention relates to novel compositions and methods of using maribavir which enhance its effectiveness in medical therapy, as well as to maribavir isomers and methods of use thereof for counteracting the potentially adverse effects of maribavir isomerization in vivo in the event it occurs.
    Type: Grant
    Filed: October 12, 2016
    Date of Patent: November 26, 2019
    Assignee: Shire ViroPharma Incorporated
    Inventor: John D. Peabody, III
  • Compositions and methods useful for the treatment of neuromyelitis optica spectrum disorders
    Patent number: 10272142
    Abstract: Compositions and methods useful for the treatment of neuromyelitis optica (NMO) or neuromyelitis optica spectrum disorder (NMOSD) are disclosed.
    Type: Grant
    Filed: November 12, 2014
    Date of Patent: April 30, 2019
    Assignee: SHIRE VIROPHARMA INCORPORATED
    Inventors: Colin Broom, Jeffrey Dayno
  • C1-INH compositions and methods for the prevention and treatment of disorders associated with C1 esterase inhibitor deficiency
    Patent number: 10201595
    Abstract: Compositions and methods for the treatment and/or prevention of disorders associated with C1 esterase inhibitor deficiency are disclosed.
    Type: Grant
    Filed: December 11, 2017
    Date of Patent: February 12, 2019
    Assignee: Shire ViroPharma Incorporated
    Inventors: Stephen Ruddy, Mark Cornell Manning, Ryan Erik Holcomb
  • C1-INH compositions and methods for the prevention and treatment of disorders associated with C1 esterase inhibitor deficiency
    Patent number: 10130690
    Abstract: Compositions and methods for the treatment and/or prevention of disorders associated with C1 esterase inhibitor deficiency are disclosed.
    Type: Grant
    Filed: December 11, 2017
    Date of Patent: November 20, 2018
    Assignee: Shire ViroPharma Incorporated
    Inventors: Stephen Ruddy, Mark Cornell Manning, Ryan Erik Holcomb
  • C1-INH compositions and methods for the prevention and treatment of disorders associated with C1 esterase inhibitor deficiency
    Patent number: 10105423
    Abstract: Compositions and methods for the treatment and/or prevention of disorders associated with C1 esterase inhibitor deficiency are disclosed.
    Type: Grant
    Filed: December 11, 2017
    Date of Patent: October 23, 2018
    Assignee: Shire ViroPharma Incorporated
    Inventors: Stephen Ruddy, Mark Cornell Manning, Ryan Erik Holcomb
  • C1-INH compositions and methods for the prevention and treatment of disorders associated with C1 esterase inhibitor deficiency
    Patent number: 10080788
    Abstract: Compositions and methods for the treatment and/or prevention of disorders associated with C1 esterase inhibitor deficiency are disclosed.
    Type: Grant
    Filed: December 11, 2017
    Date of Patent: September 25, 2018
    Assignee: Shire ViroPharma Incorporated
    Inventors: Stephen Ruddy, Mark Cornell Manning, Ryan Erik Holcomb
  • Methods of treating antibody-mediated rejection in organ transplant patients with C1-esterase inhibitor
    Patent number: 9895428
    Abstract: A method and composition for treating or preventing antibody-mediated rejection (AMR) of a transplanted organ are provided.
    Type: Grant
    Filed: November 21, 2014
    Date of Patent: February 20, 2018
    Assignee: Shire Viropharma Incorporated
    Inventors: Colin Broom, Marc E. Uknis
  • C1-INH compositions and methods for the prevention and treatment of disorders associated with C1 esterase inhibitor deficiency
    Patent number: 9616111
    Abstract: Compositions and methods for the treatment and/or prevention of disorders associated with C1 esterase inhibitor deficiency are disclosed.
    Type: Grant
    Filed: September 15, 2015
    Date of Patent: April 11, 2017
    Assignee: Shire ViroPharma Incorporated
    Inventors: Stephen Ruddy, Mark Cornell Manning, Ryan Erik Holcomb