Abstract: The present invention provides a new process for preparation of imidazo-tetrazine class of chemical entity useful as anticancer agent. The present invention provides a commercially and economically viable process for preparation of Temozolomide of formula (VI). Present invention also relates to an intermediate compound of formula (III) and its preparation useful in the process for preparing Temozolomide.
Abstract: The present invention provides a new process for preparation of imidazo-tetrazine class of chemical entity useful as anticancer agent. The present invention provides a commercially and economically viable process for preparation of Temozolomide of formula (VI). Present invention also relates to an intermediate compound of formula (III) and its preparation useful in the process for preparing Temozolomide.
Abstract: The present invention provides process for preparation of highly pure Fingolimod hydrochloride (I), without involving the use of column chromatographic purification in the entire process. Fingolimod hydrochloride (I) obtained by the process of present invention may be useful as active pharmaceutical ingredient in pharmaceutical compositions for the treatment of autoimmune related disorder including multiple sclerosis.
Abstract: The present invention provides to an improved process for the preparation of highly pure Erlotinib hydrochloride of formula (I) The substantially pure Erlotinib hydrochloride (I) obtained by improved process of the present invention is having purity of greater than 99.8% (% w/w by HPLC). Erlotinib hydrochloride is useful in the treatment of cancer more particularly in the treatment of lung cancer and pancreatic cancer.
Type:
Application
Filed:
January 23, 2021
Publication date:
July 28, 2022
Applicant:
SHIVALIK RASAYAN LIMITED
Inventors:
AKSHAY KANT CHATURVEDI, SATYENDRA SINGH, BIJAN PANDA
Abstract: The present invention relates to a process for the preparation of the active pharmaceutical ingredient Fingolimod Hydrochloride (I) and its highly pure intermediate [2-acetamido-2-(acetyloxy methyl)-4-phenylbutyl] acetate(II)
Abstract: The present invention provides process for preparation of highly pure Fingolimod hydrochloride (I), without involving the use of column chromatographic purification in the entire process. Fingolimod hydrochloride (I) obtained by the process of present invention may be useful as active pharmaceutical ingredient in pharmaceutical compositions for the treatment of autoimmune related disorder including multiple sclerosis.