Patents Assigned to Shjonogi & Co., Ltd.
  • Method for producing hydroxylated adaivjantane using cytochrome P450
    Patent number: 8383381
    Abstract: Disclosed is a method for producing a hydroxylated form of a compound having an adamantane skeleton, which is useful as an intermediate for functional resins and pharmaceutical products, with high yield and at low cost. Specifically, a hydroxylated form of a compound having an adamantane skeleton can be obtained by using cytochrome P450. More specifically, an N-(5-hydroxy-2-adamantyl)-benzamide derivative can be produced by hydroxylating an N-(2-adamantyl)-benzamide derivative.
    Type: Grant
    Filed: September 25, 2008
    Date of Patent: February 26, 2013
    Assignee: Shjonogi & Co., Ltd.
    Inventors: Taijiro Tomikawa, Yuuichi Mitsuda