Abstract: DNA encoding human neuronal nicotinic acetylcholine receptor .alpha..sub.2 subunits, mammalian and amphibian cells containing said DNA, and methods for producing such subunits are provided. In addition, combinations of subunits (i.e., .alpha..sub.2, plus .alpha..sub.1, .alpha..sub.3, .alpha..sub.4, and/or .alpha..sub.7 subunits in combination with .beta..sub.2, .beta..sub.3 and/or .beta..sub.4 subunits) are provided.
Type:
Grant
Filed:
June 20, 1995
Date of Patent:
September 1, 1998
Assignee:
SIBIA Neuroscience, Inc.
Inventors:
Kathryn J. Elliott, Steven B. Ellis, Michael M. Harpold