Abstract: The present invention relates to a solid form of a compound of Formula (I), a method for preparing the solid form, a pharmaceutical composition comprising the solid form, and the use of the solid form in the treatment of a disease involving abnormal cell proliferation or a viral infectious disease.
Abstract: The present invention relates to a dihydropyrimidine compound having an antiviral activity, a pharmaceutical composition comprising same, a preparation method therefor and the uses thereof in the prevention or treatment of viral diseases including, but not limited to, Hepatitis A, Hepatitis B, Hepatitis C, influenza, herpes and acquired immunodeficiency syndrome (AIDS).
Abstract: The present invention provides an anti-ErbB2 antibody-drug conjugate, a composition comprising the conjugate, a method for preparing the conjugate, use of the conjugate.
Abstract: The present invention relates to an azetidine derivative for use as a Janus kinase (JAK) inhibitor, a drug composition comprising same, a preparation method therefor, and a use thereof in the treatment of JAK-related diseases comprising, for example, inflammatory diseases, autoimmune diseases, and cancers.
Inventors:
YINONG XIE, Zejin YOU, Zhiwen DENG, Jun ZHU, Ao WANG, Yan FENG, Dong LONG, Hong ZENG, Hongmei SONG, Qijun YE, Wei QI, Donghai SU, Lichun WANG, Jingyi WANG
Abstract: The present invention relates to an azetidine derivative for use as a Janus kinase (JAK) inhibitor, a drug composition comprising same, a preparation method therefor, and a use thereof in the treatment of JAK-related diseases comprising, for example, inflammatory diseases, autoimmune diseases, and cancers.
Inventors:
Yinong Xie, Zejin You, Zhiwen Deng, Jun Zhu, Ao Wang, Yan Feng, Dong Long, Hong Zeng, Hongmei Song, Qijun Ye, Wei Qi, Donghai Su, Lichun Wang, Jingyi Wang
Abstract: The present invention relates to a benzodiazepine derivative of Formula I as a short-acting anesthetic, a pharmaceutical composition comprising the same, a kit comprising the same, a preparation method thereof, an method of anesthesia using the same and use thereof in the manufacture of an anesthetic medicament.
Abstract: The present invention relates to an azetidine derivative for use as a Janus kinase (JAK) inhibitor, a drug composition comprising same, a preparation method therefor, and a use thereof in the treatment of JAK-related diseases comprising, for example, inflammatory diseases, autoimmune diseases, and cancers.
Inventors:
Yinong XIE, Zejin YOU, Zhiwen DENG, Jun ZHU, Ao WANG, Yan FENG, Dong LONG, Hong ZHENG, Hongmei SONG, Qijun YE, Wei Qi, Donghai SU, Lichun WANG, Jingyi WANG
Abstract: The present invention relates to a novel compound of 4?-thionucleoside, a preparation method therefor, a pharmaceutical composition comprising the same and an application thereof. Specifically, the present invention relates to a phosphamide derivative of 4?-thionucleoside, a preparation method therefor, a pharmaceutical composition comprising the same, a use thereof in the preparation of a medicine for preventing or treating abnormal cell proliferation diseases (for example, tumors or cancers and related diseases) or virus infectious diseases, and a method of using the same for preventing or treating abnormal cell proliferation diseases (for example, tumors or cancers and related diseases) or virus infectious diseases.
Inventors:
Hong YE, Gang LIU, Nan YU, Hong ZENG, Mingliang ZHAO, Yan QING, Hua DENG, Wenjia LI, Donghong LI, Donghai SU, Wei ZHONG, Shaohua LI, Xunwei WU, Lichun WANG, Jingyi WANG