Abstract: The invention offers a method of hydrogenating camptothecin in inert solvent in the presence of nickel catalyst, whereby selective hydrogenation of camptothecin can be very efficiently accomplished using the low-cost catalyst.
Type:
Grant
Filed:
May 22, 2009
Date of Patent:
October 30, 2012
Assignees:
Sichuan Xieli Pharmaceutical Co., Ltd., MicroBiopharm Japan Co., Ltd.
Inventors:
Asako Toyoda, Hazuki Nagai, George Ng'ang'a Wanyoike
Abstract: The invention offers a method of hydrogenating camptothecin in inert solvent in the presence of nickel catalyst, whereby selective hydrogenation of camptothecin can be very efficiently accomplished using the low-cost catalyst.