Patents Assigned to Sicor, Inc.
  • Patent number: 9718829
    Abstract: Provided are crystalline forms of N-[4-[2-(2-amino-4, 7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]ben-zoyl]-L-glutamic acid, pemetrexed diacid, and processes for the preparation thereof.
    Type: Grant
    Filed: November 23, 2016
    Date of Patent: August 1, 2017
    Assignee: Sicor Inc.
    Inventors: Jonathan Busolli, Nicola Diulgheroff, Csilla Nemethne Racz, Moran Pirkes, Alessandro Pontiroli, Marco Villa, Judith Aronhime
  • Patent number: 9562050
    Abstract: Provided are crystalline forms of N-[4-[2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]ben-zoyl]-L-glutamic acid, pemetrexed diacid, and processes for the preparation thereof.
    Type: Grant
    Filed: September 16, 2015
    Date of Patent: February 7, 2017
    Assignee: Sicor, Inc.
    Inventors: Jonathan Busolli, Nicola Diulgheroff, Csilla Nemethne Racz, Moran Pirkes, Alessandro Pontiroli, Marco Villa, Judith Aronhime
  • Patent number: 9156841
    Abstract: Provided are crystalline forms of N-[4-[2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid, pemetrexed diacid, and processes for the preparation thereof.
    Type: Grant
    Filed: March 23, 2011
    Date of Patent: October 13, 2015
    Assignee: Sicor Inc.
    Inventors: Jonathan Busolli, Nicola Diulgheroff, Csilla Nemethne Racz, Moran Pirkes, Alessandro Pontiroli, Marco Villa, Judith Aronhime
  • Patent number: 9108962
    Abstract: This invention relates to novel crystalline forms of tiotropium bromide, processes for preparing them, and their use in pharmaceutical formulations.
    Type: Grant
    Filed: June 16, 2014
    Date of Patent: August 18, 2015
    Assignee: Sicor, Inc.
    Inventors: Nicola Diulgheroff, Francesca Scarpitta, Alessandro Pontiroli, Adrienne Kovacsne-Mezei, Judith Aronhime, Alexandr Jegorov
  • Patent number: 8846926
    Abstract: This invention relates to novel crystalline forms of tiotropium bromide, processes for preparing them, and their use in pharmaceutical formulations.
    Type: Grant
    Filed: December 28, 2011
    Date of Patent: September 30, 2014
    Assignee: Sicor Inc.
    Inventors: Nicola Diulgheroff, Francesca Scarpitta, Alessandro Pontiroli, Adrienne Kovacsne-Mezei, Judith Aronhime, Alexandr Jegorov
  • Patent number: 8629152
    Abstract: Provided are processes for the preparation of lyophilized pharmaceutically acceptable salts of pemetrexed diacid, in particular, pemetrexed disodium salt, directly from pemetrexed diacid or salts thereof, i.e., without isolating the obtained pemetrexed salt prior to lyophilizing it.
    Type: Grant
    Filed: August 14, 2007
    Date of Patent: January 14, 2014
    Assignee: Sicor, Inc.
    Inventors: Jonathan Busolli, Nicola Diulgheroff, Moran Pirkes, Alessandro Pontiroli, Marco Villa, Zvi Harel
  • Patent number: 8378103
    Abstract: The invention is directed to improved processes for preparing Tiotropium bromide.
    Type: Grant
    Filed: January 4, 2010
    Date of Patent: February 19, 2013
    Assignee: Sicor, Inc.
    Inventors: Jonathan Busolli, Nicola Diulgheroff, Francesca Scarpitta, Roberta Volonte, Alessandro Pontiroli
  • Patent number: 8362245
    Abstract: Provided are processes for preparing intermediates of pemetrexed.
    Type: Grant
    Filed: June 30, 2011
    Date of Patent: January 29, 2013
    Assignee: Sicor Inc.
    Inventors: Nicola Diulgheroff, Moran Pirkes, Alessandro Pontiroli, Marco Zrinski Villa
  • Patent number: 8344143
    Abstract: The invention is directed to improved processes for preparing Tiotropium bromide.
    Type: Grant
    Filed: December 23, 2009
    Date of Patent: January 1, 2013
    Assignee: Sicor, Inc.
    Inventors: Jonathan Busolli, Nicola Diulgheroff, Francesca Scarpitta, Roberta Volonte, Alessandro Pontiroli
  • Patent number: 8217061
    Abstract: Provided are sorafenib hemi-tosylate, polymorphs thereof, polymorphs of sorafenib tosylate, preparation thereof and pharmaceutical compositions thereof.
    Type: Grant
    Filed: January 19, 2009
    Date of Patent: July 10, 2012
    Assignee: Sicor Inc.
    Inventors: Ale{hacek over (s)} Gavenda, Alexandr Jegorov, Pierluigi Rossetto, Peter Lindsay MacDonald, Augusto Canavesi
  • Publication number: 20120165364
    Abstract: This invention relates to novel crystalline forms of tiotropium bromide, processes for preparing them, and their use in pharmaceutical formulations.
    Type: Application
    Filed: March 5, 2012
    Publication date: June 28, 2012
    Applicant: SICOR INC.
    Inventors: Nicola Diulgheroff, Francesca Scarpitta, Alessandro Pontiroli, Adrienne Kovacsne-Mezei, Judith Aronhime, Alexandr Jegorov
  • Publication number: 20120108625
    Abstract: This invention relates to novel crystalline forms of tiotropium bromide, processes for preparing them, and their use in pharmaceutical formulations.
    Type: Application
    Filed: December 28, 2011
    Publication date: May 3, 2012
    Applicant: SICOR INC.
    Inventors: Nicola DIULGHEROFF, Francesca SCARPITTA, Alessandro PONTIROLI, Adrienne KOVACSNE-MEZEI, Judith ARONHIME, Alexandr JEGOROV
  • Patent number: 8163913
    Abstract: This invention relates to novel crystalline forms of tiotropium bromide, processes for preparing them, and their use in pharmaceutical formulations.
    Type: Grant
    Filed: December 19, 2006
    Date of Patent: April 24, 2012
    Assignee: Sicor Inc.
    Inventors: Nicola Diulgheroff, Francesca Scarpitta, Alessandro Pontiroli, Adrienne Kovacsne-Mezei, Judith Aronhime, Alexandr Jegorov
  • Patent number: 8088919
    Abstract: Provided are crystalline forms of N-[4-[2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid, pemetrexed diacid, and processes for the preparation thereof.
    Type: Grant
    Filed: August 14, 2007
    Date of Patent: January 3, 2012
    Assignee: Sicor Inc.
    Inventors: Jonathan Busolli, Nicola Diulgheroff, Csilla Nemethne Racz, Moran Pirkes, Alessandro Pontiroli, Marco Villa, Judith Aronhime
  • Patent number: 8067421
    Abstract: Solvates and crystalline forms of imatinib mesylate are described. Further, methods for preparing such solvates and crystalline forms of imatinib mesylate are described.
    Type: Grant
    Filed: April 27, 2007
    Date of Patent: November 29, 2011
    Assignee: Sicor Inc.
    Inventors: Alexandr Jegorov, Miloslav Chudík, Judith Aronhime, Ale{hacek over (s)} Gavenda, Ji{hacek over (r)}í Faustmann
  • Publication number: 20110263851
    Abstract: Provided are processes for preparing intermediates of pemetrexed.
    Type: Application
    Filed: June 30, 2011
    Publication date: October 27, 2011
    Applicant: SICOR INC.
    Inventors: Nicola DIULGHEROFF, Moran PIRKES, Alessandro PONTIROLI, Marco VILLA
  • Publication number: 20110196155
    Abstract: Provided are crystalline forms of N-[4-[2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid, pemetrexed diacid, and processes for the preparation thereof.
    Type: Application
    Filed: March 23, 2011
    Publication date: August 11, 2011
    Applicant: SICOR INC.
    Inventors: Jonathan BUSOLLI, Nicola DIULGHEROFF, Csilla Nemethne Racz, Moran PIRKES, Alessandro PONTIROLI, Marco VILLA, Judith ARONHIME
  • Patent number: 7994180
    Abstract: The invention provides intermediates of pemetrexed of formula VI and processes for the preparation thereof.
    Type: Grant
    Filed: August 14, 2007
    Date of Patent: August 9, 2011
    Assignee: Sicor Inc.
    Inventors: Nicola Diulgheroff, Moran Pirkes, Alessandro Pontiroli, Marco Villa
  • Patent number: 7977348
    Abstract: Solvates and crystalline forms of imatinib mesylate are described. Further, methods for preparing such solvates and crystalline forms of imatinib mesylate are described. The structure diagram below shows the chemical structure of imatinib mesylate.
    Type: Grant
    Filed: April 17, 2008
    Date of Patent: July 12, 2011
    Assignee: Sicor Inc.
    Inventors: Alexandr Jegorov, Miloslav Chudík, Judith Aronhime, Ale{hacek over (s)} Gavenda, Ji{hacek over (r)}í Faustmann
  • Patent number: 7790910
    Abstract: Processes useful in the preparation of pharmaceutical compounds such as fulvestrant and processes for the preparation of fulvestrant.
    Type: Grant
    Filed: July 27, 2005
    Date of Patent: September 7, 2010
    Assignee: Sicor Inc.
    Inventors: Peter Lindsay MacDonald, Ettore Bigatti, Pierluigi Rossetto