Patents Assigned to Sicor Societa Italiana Corticosteroidi S.p.A.
  • Process for the conversion of daunorubicin into doxorubicin
    Patent number: 5008380
    Abstract: An improved process for the preparation of doxorubicin, by means of hydrolysis of a doxorubicin ester of a dicarboxylic acid, in acid medium.
    Type: Grant
    Filed: November 9, 1988
    Date of Patent: April 16, 1991
    Assignee: Sicor Societa 'Italiana Corticosteroidi S.p.A.
    Inventors: Gaetano Palladino, Peter MacDonald, Ettore Bigatti
  • 16,17 acetals of pregnane derivatives and pharmaceutical compositions containing them
    Patent number: 4835145
    Abstract: A compound exhibiting anti-inflammatory properties having the formula ##STR1## in which X is H, Hal or CH.sub.3 COO--; R.sub.1 is CH.sub.3 (CH.sub.2).sub.2 CH--; and R.sub.2 and R.sub.3 are separately H or Hal; and a pharmaceutical composition containing the same.
    Type: Grant
    Filed: January 2, 1987
    Date of Patent: May 30, 1989
    Assignee: Sicor Societa' Italiana Corticosteroidi S.p.A.
    Inventor: Peter MacDonald
  • Process for the preparation of 16,17 acetals of pregnane derivatives
    Patent number: 4695625
    Abstract: A process for the preparation of 16,17 acetals of pregnane derivatives by trans-ketalization of 16,17-acetonides is described.In the instance of the preparation of 16.alpha.,17.alpha.-butylidenedioxy-11.beta.,21-dihydroxypregna-1,4-diene- 3,20-dione, a compound having useful therapeutic properties, known also as budesonide, it is possible to obtain the more active epimer with high selectivity and remarkable economic advantages in comparison with the known methods.New 16,17 acetals of pregnane derivatives, which can be prepared by the method of the invention, are also described.
    Type: Grant
    Filed: May 30, 1985
    Date of Patent: September 22, 1987
    Assignee: Sicor Societa Italiana Corticosteroidi S.p.A.
    Inventor: Peter Macdonald