Abstract: The invention relates to a novel pharmaceutical combination. The inventive pharmaceutical composition comprises a combination of tenatoprazole and one or more anti-inflammatory agents selected from non-steroid anti-inflammatory agents and cyclooxygenase-2 inhibitors. The invention is suitable for the treatment of painful and inflammatory manifestations.
Abstract: The invention relates to a novel pharmaceutical combination. The inventive pharmaceutical composition, which is intended for the treatment of pathologies linked to gastric hyperacidity, comprises a combination of tenatoprazole and one or more histamine H2-receptor antagonists preferably selected from cimetidine, ranitidine, famotidine and nizatidine. The invention is particularly suitable for the treatment of duodenal and gastric ulcers and the symptoms of, and lesions caused by, gastroesophageal reflux.
Abstract: The invention relates to a novel therapeutic application of tenatoprazole. Tenatoprazole and the salts thereof can be used in the production of a medicament for the treatment of atypical and esophageal symptoms of gastroesophageal reflux, gastrorrhagia and dyspepsia.
Abstract: The invention relates to a novel pharmaceutical combination. The inventive pharmaceutical composition comprises a combination of tenatoprazole and one or more anti-inflammatory agents selected from non-steroid anti-inflammatory agents and cyclooxygenase-2 inhibitors. The invention is suitable for the treatment of painful and inflammatory manifestations.
Abstract: The invention relates to enantiomer (?) of tentoprazole. The inventive enantiomer (?) of tenatoprazole, or (?)-5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]sulfinyl]imidazol[4,5-b]pyridine exhibits improved pharmacokinetic properties which make it possible to use a once a day posology of a drug for relevant indications. The enantiomer (?) of tentoprazole can be used for treating digestive pathologies.
Abstract: The present invention relates to S-tenatoprazole monohydrated sodium salt, represented by the following formula and the use thereof in therapy for the treatment of digestive diseases.
Type:
Grant
Filed:
June 17, 2005
Date of Patent:
July 22, 2008
Assignee:
Sidem Pharma
Inventors:
Avraham Cohen, François Schutze, Suzy Charbit, Frédéric Martinet, Hervé Ficheux, Michel Homerin
Abstract: The invention relates to enantiomer (?) of tentoprazole. The inventive enantiomer (?) of tenatoprazole, or (?)-5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]sulfinyl]imidazol[4,5-b]pyridine exhibits improved pharmacokinetic properties which make it possible to use a once a day posology of a drug for relevant indications. Said invention can be used for curing digestive pathologies.
Type:
Grant
Filed:
December 16, 2003
Date of Patent:
April 25, 2006
Assignee:
Sidem Pharma
Inventors:
Avraham Cohen, Suzy Charbit, François Schutze, Hervé Ficheux, Michel Homerin, Alain Taccoen