Patents Assigned to Siemens Healthcare Diagnostics Holding GmbH
  • Publication number: 20160174875
    Abstract: An assembly for the extraction of respiratory gas samples may include a container for receiving a respiratory gas sample, a piston arranged in the container in a movable and gas-sealing manner, and a gas feed into the container, which gas feed can be connected to a mouthpiece.
    Type: Application
    Filed: August 6, 2014
    Publication date: June 23, 2016
    Applicants: Siemens Aktiengesellschaft, Siemens Healthcare Diagnostics Holding GmbH
    Inventors: Brigitte FÖRSTER, Andreas KAPPEL, Erhard MAGORI, Roland POHLE, Oliver von SICARD
  • Publication number: 20150184223
    Abstract: The invention relates to a method and kit for enriching miRNA nucleic acids molecules of interest in a sampe by selective removal of nucleic acid species, in particular miRNA species, which are not of interest. The invention is based on the surprizing and previously unknown information that only a few individual miRNA species make up the majority of all miRNA species in a sample. Selective removal of these species prior to detection of miRNA nucleic acids molecules will improve assay time, assay sensitivity, and reproducibility.
    Type: Application
    Filed: June 26, 2013
    Publication date: July 2, 2015
    Applicants: SIEMENS HEALTHCARE DIAGNOSTICS HOLDING GMBH, SIEMENS AKTIENGESELLSCHAFT
    Inventors: Andreas Keller, Andreas Kappel, Cord Friedrich Stähler
  • Publication number: 20150111772
    Abstract: The invention relates to methods for diagnosing multiple sclerosis with miRNA markers. Diagnosis of multiple sclerosis (MS) can be challenging in patients with atypical presentations and during a first neurological deficit possibly related to inflammatory demyelination. Towards the identification of biomarkers for diagnosis of MS, a comprehensive analysis of miRNA expression patterns was obtained. Significantly deregulated miRNAs were identified, which have previously not been related to MS according to the microRNA disease database. These miRNAs could potentially serve as future diagnostic biomarkers for MS and help in diagnosis, monitoring disease activity, and evaluation of treatment responses in patients with MS.
    Type: Application
    Filed: April 18, 2013
    Publication date: April 23, 2015
    Applicant: Siemens Healthcare Diagnostics Holding GmbH
    Inventors: Andreas Keller, Eckart Meese, Cord Friedrich Stähler, Andreas Kappel, Petra Leidinger, Christina Backes