Abstract: Provided herein are methods and systems for training and executing an AI model to generate a predicted dose map. In an example, a method comprises generating a training dataset comprising at least a medical image, structure mask(s) for structure(s) within the medical image, an indication of radiotherapy treatment modality, and beam geometry associated with a set of patients, wherein the training dataset comprises data associated with treatments implemented using at least one of volumetric modulated arc therapy or intensity-modulated radiotherapy modalities; training an artificial intelligence model using the training dataset, such that the artificial intelligence model is configured to receive data associated with a new patient and generate a predicted dose map for the new patient indicating dosage received by one or more internal structures of the new patient; executing the artificial intelligence model for the new patient to receive the predicted dose map for the new patient; and outputting the result.