Patents Assigned to Sierra Diagnostics, Inc.
  • Methods and reagents for preservation of DNA in bodily fluids
    Patent number: 6458546
    Abstract: A method and system are provided for preserving nucleic acids in a bodily fluid, such as urine, blood, blood serum, and amniotic fluid. The preservative includes an amount of a divalent metal chelator selected from ethylenediaminetetraacetic acid (EDTA), [ethylenebis(oxyethylenenitrilo)]tetraacetic acid (EGTA) and 1,2-bis(2-aminophenoxy)ethane-N,N,N′, N′-tetraacetic acid (BAPTA), or salts thereof in the range of from about 0.001M to 0.1M; and an amount of at least one chelator enhancing component selected from lithium chloride, guanidine, sodium salicylate, sodium perchlorate, and sodium thiocyanate in the range of from about 0.1M to 2M.
    Type: Grant
    Filed: June 15, 2001
    Date of Patent: October 1, 2002
    Assignee: Sierra Diagnostics, Inc.
    Inventor: Tony Baker
  • Methods and reagents for preservation of DNA in bodily fluids
    Publication number: 20020102570
    Abstract: A method and system are provided for preserving nucleic acids in a bodily fluid, such as urine, blood, blood serum, and amniotic fluid. The preservative includes an amount of a divalent metal chelator selected from ethylenediaminetetraacetic acid (EDTA), [ethylenebis(oxyethylenenitrilo)]tetraacetic acid (EGTA) and 1,2-bis(2-aminophenoxy) ethane-N,N,N′,N′-tetraacetic acid (BAPTA), or salts thereof in the range of from about 0.001M to 0.1M; and an amount of at least one chelator enhancing component selected from lithium chloride, guanidine, sodium salicylate, sodium perchlorate, and sodium thiocyanate in the range of from about 0.1M to 2M.
    Type: Application
    Filed: June 15, 2001
    Publication date: August 1, 2002
    Applicant: Sierra Diagnostics, Inc.
    Inventor: Tony Baker
  • Methods and reagents for preservation of DNA in bodily fluids
    Publication number: 20020037512
    Abstract: A method and system are provided for preserving nucleic acids in a bodily fluid, such as urine, blood, blood serum, and amniotic fluid. The preservative includes an amount of a divalent metal chelator selected from ethylenediaminetetraacetic acid (EDTA), [ethylenebis(oxyethylenenitrilo)]tetraacetic acid (EGTA) and 1,2-bis(2-aminophenoxy) ethane-N,N,N′,N′-tetraacetic acid (BAPTA), or salts thereof in the range of from about 0.001M to 0.1M; and an amount of at least one chelator enhancing component selected from lithium chloride, guanidine, sodium salicylate, sodium perchlorate, and sodium thiocyanate in the range of from about 0.1M to 2M.
    Type: Application
    Filed: March 13, 2001
    Publication date: March 28, 2002
    Applicant: Sierra Diagnostics, Inc.
    Inventor: Tony Baker