Abstract: The use of 7-ter-butoxyiminomethylcamptothecin is described in the preparation of a medicament useful for the treatment of uterine neoplasms, particularly cancer of the endometrium and of the neck of the womb.
Type:
Grant
Filed:
June 8, 2005
Date of Patent:
April 20, 2010
Assignee:
Sigma-Tau Farmaceutiche Riunite, S.p.A.
Inventors:
Paolo Carminati, Marco Corsi, Claudio Zanna, Franco Cavalli, Luca Gianni, Cristiana Sessa
Abstract: Esters of L-carnitine and alkanoyl L-carnitines are described which can be used as cationic lipids for the intracellular delivery of pharmacologically active compounds. New esters of L-carnitine and alkanoyl L-carnitines of formula (I) are also disclosed wherein the R groups are as defined in the description.
Abstract: Indole derivatives of Formula (I+A) having antitumour and chemosensitizing activity are described. Also described are pharmaceutical compositions containing the above-mentioned compounds, for the treatment of tumours.
Type:
Application
Filed:
May 31, 2006
Publication date:
August 28, 2008
Applicant:
SIGMA-TAU FARMACEUTICHE RIUNITE S.P.A.
Inventors:
Claudio Pisano, Gianfranco Battistuzzi, Maria Di Marzo, Giuseppe Giannini, Mauro Marzi, Loredana Vesci, Franco Zunino
Abstract: Cinnamic and phenylpropiolic acid derivatives of formula (I) having antitumour and chemo sensitizing activity are described. Also described are pharmaceutical compositions containing the above-mentioned compounds, for the treatment of tumours.
Type:
Application
Filed:
May 31, 2006
Publication date:
August 14, 2008
Applicant:
SIGMA-TAU FARMACEUTICHE RIUNITE S.P.A.
Inventors:
Claudio Pisano, Gianfranco Battistuzzi, Maria Di Marzo, Giuseppe Giannini, Mauro Marzi, Loredana Vesci, Franco Zunino, Ricaardo Pezzi
Abstract: A new crystalline form of 1-methyl-5-p-toluoylpyrrole-2-acetamidoacetic acid guaiacyl ester, a process for its preparation and pharmaceutical compositions endowed of anti-inflammatory, analgesic and antipyretic activity containing same are disclosed.