Patents Assigned to SIGNALCHEM LIFESCIENCES CORPORATION
  • Combination therapy for treating blood cancer
    Patent number: 12097194
    Abstract: Provided herein are combination therapies for treating blood cancer, in particular, acute myeloid leukemia, by concurrently targeting Axl and BCL-2.
    Type: Grant
    Filed: September 18, 2019
    Date of Patent: September 24, 2024
    Assignee: SIGNALCHEM LIFESCIENCES CORPORATION
    Inventors: Zaihui Zhang, Xiaoyan Jiang, Katharina Rothe, Xiaojia Niu
  • Aminopyridine derivatives as TAM family kinase inhibitors
    Patent number: 11034686
    Abstract: Provided herein are aminopyridine derivatives and pharmaceutical compositions that are useful as TAM family kinase inhibitors.
    Type: Grant
    Filed: June 11, 2020
    Date of Patent: June 15, 2021
    Assignee: SignalChem Lifesciences Corporation
    Inventor: Zaihui Zhang
  • Aminopyridine derivatives as TAM family kinase inhibitors
    Patent number: 11034685
    Abstract: Provided herein are aminopyridine derivatives and pharmaceutical compositions that are useful as TAM family kinase inhibitors.
    Type: Grant
    Filed: June 11, 2020
    Date of Patent: June 15, 2021
    Assignee: SignalChem Lifesciences Corporation
    Inventor: Zaihui Zhang
  • Aminopyridine derivatives as TAM family kinase inhibitors
    Patent number: 10723725
    Abstract: Provided herein are aminopyridine derivatives and pharmaceutical compositions that are useful as TAM family kinase inhibitors.
    Type: Grant
    Filed: January 22, 2019
    Date of Patent: July 28, 2020
    Assignee: SignalChem Lifesciences Corporation
    Inventor: Zaihui Zhang
  • Aryl sulfonamide compounds as carbonic anhydrase inhibitors and their therapeutic use
    Patent number: 10562859
    Abstract: Disclosed herein are compounds having the following structure useful as inhibitors of carbonic anhydrase IX (CAIX) and XII, and particularly useful for reducing or eliminating metastases see Formula (I).
    Type: Grant
    Filed: July 1, 2016
    Date of Patent: February 18, 2020
    Assignee: SIGNALCHEM LIFESCIENCES CORPORATION
    Inventor: Zaihui Zhang
  • Aminopyridine derivatives as TAM family kinase inhibitors
    Patent number: 10233176
    Abstract: Provided herein are aminopyridine derivatives and pharmaceutical compositions that are useful as TAM family kinase inhibitors.
    Type: Grant
    Filed: November 26, 2014
    Date of Patent: March 19, 2019
    Assignee: SIGNALCHEM LIFESCIENCES CORPORATION
    Inventor: Zaihui Zhang
  • Carbonic anhydrase IX-related markers and use thereof
    Patent number: 10195174
    Abstract: The present disclosure provides methods for detecting the presence of a cancer stem cell and their use in cancer prognosis, evaluating risk of cancer metastasis, identifying or validating drug candidates, and determining treatment efficacy. It also provides kits useful for detecting the presence of cancer stem cells as well as methods of treating cancer using CAIX inhibitors.
    Type: Grant
    Filed: October 24, 2012
    Date of Patent: February 5, 2019
    Assignees: SIGNALCHEM LIFESCIENCES CORPORATION, BRITISH COLUMBIA CANCER AGENCY BRANCH
    Inventors: Paul C. McDonald, Frances E. Lock, Shoukat Dedhar