Patents Assigned to Signatures, Inc.
  • Methods for evaluating Alzheimer's disease and disease severity
    Patent number: 9758830
    Abstract: A method for diagnosing and/or evaluating dementia severity in a subject suspected of having or having dementia is provided the method comprising: a) obtaining a test cell sample from the subject, b) assaying the test cell sample to determine a telomere organization signature of the test sample, the telomere organization signature comprising one or more parameters selected from: i) telomere aggregates; ii) telomere number; iii) telomere length and telomere number; iv) telomere aggregates, telomere length and telomere numbers; c) comparing the test cell sample telomere organization signature to a control or one or more predetermined reference signatures; and d) diagnosing whether the subject has dementia and/or the dementia severity according to the test sample telomere organization signature.
    Type: Grant
    Filed: September 20, 2014
    Date of Patent: September 12, 2017
    Assignee: 3D SIGNATURES INC.
    Inventors: Sabine Mai, Angeles Garcia
  • Methods of detecting and monitoring cancer using 3D analysis of centromeres
    Patent number: 8849579
    Abstract: The present application relates to a method of detecting and monitoring cancer or precancer in a cell using three-dimensional analysis to assess centromere organization. In addition, the application relates to a method and system for characterizing the 3D organization of centromeres.
    Type: Grant
    Filed: September 28, 2007
    Date of Patent: September 30, 2014
    Assignee: 3D Signatures Inc.
    Inventors: Sabine Mai, Yuval Garini, Rahul Sarkar, Bartholomeus J. Vermolen
  • Cocktail table with foldable and extendable two-piece top
    Patent number: D577930
    Type: Grant
    Filed: June 25, 2007
    Date of Patent: October 7, 2008
    Assignee: American Signature, Inc.
    Inventor: David W. Thompson
  • Headboard component
    Patent number: D577931
    Type: Grant
    Filed: September 18, 2007
    Date of Patent: October 7, 2008
    Assignee: American Signature, Inc.
    Inventor: David W. Thompson
  • Furniture knob
    Patent number: D577982
    Type: Grant
    Filed: September 17, 2007
    Date of Patent: October 7, 2008
    Assignee: American Signature, Inc.
    Inventor: David W. Thompson
  • Footboard
    Patent number: D578810
    Type: Grant
    Filed: October 17, 2007
    Date of Patent: October 21, 2008
    Assignee: American Signature, Inc.
    Inventor: David W. Thompson
  • Drawer pull
    Patent number: D581767
    Type: Grant
    Filed: October 8, 2007
    Date of Patent: December 2, 2008
    Assignee: American Signature, Inc.
    Inventor: David W. Thompson
  • Chair component
    Patent number: D582182
    Type: Grant
    Filed: June 25, 2007
    Date of Patent: December 9, 2008
    Assignee: American Signature, Inc.
    Inventor: David W. Thompson
  • Furniture panel
    Patent number: D582701
    Type: Grant
    Filed: October 17, 2007
    Date of Patent: December 16, 2008
    Assignee: American Signature, Inc.
    Inventor: David W. Thompson
  • Upholstered chair
    Patent number: D587473
    Type: Grant
    Filed: September 12, 2008
    Date of Patent: March 3, 2009
    Assignee: American Signature, Inc.
    Inventor: David W. Thompson
  • Sofa
    Patent number: D587479
    Type: Grant
    Filed: September 12, 2008
    Date of Patent: March 3, 2009
    Assignee: American Signature, Inc.
    Inventor: David W. Thompson
  • Ornamentation arch
    Patent number: D588382
    Type: Grant
    Filed: October 17, 2007
    Date of Patent: March 17, 2009
    Assignee: American Signature, Inc.
    Inventor: David W. Thompson
  • Lattice
    Patent number: D588383
    Type: Grant
    Filed: October 23, 2007
    Date of Patent: March 17, 2009
    Assignee: American Signature, Inc.
    Inventor: David W. Thompson
  • Chaise lounge
    Patent number: D591525
    Type: Grant
    Filed: September 12, 2008
    Date of Patent: May 5, 2009
    Assignee: American Signature, Inc.
    Inventor: David W. Thompson
  • Furniture leg cross bars
    Patent number: D591541
    Type: Grant
    Filed: February 7, 2008
    Date of Patent: May 5, 2009
    Assignee: American Signature, Inc.
    Inventor: David W. Thompson
  • Filigree design furniture component
    Patent number: D591987
    Type: Grant
    Filed: September 12, 2008
    Date of Patent: May 12, 2009
    Assignee: American Signature, Inc.
    Inventor: David W. Thompson
  • Dining chair component
    Patent number: D593346
    Type: Grant
    Filed: August 10, 2008
    Date of Patent: June 2, 2009
    Assignee: American Signature, Inc.
    Inventor: David W. Thompson
  • Dresser
    Patent number: D595975
    Type: Grant
    Filed: March 19, 2009
    Date of Patent: July 14, 2009
    Assignee: American Signature, Inc.
    Inventor: David W. Thompson
  • Furniture
    Patent number: D597346
    Type: Grant
    Filed: October 17, 2007
    Date of Patent: August 4, 2009
    Assignee: American Signature, Inc.
    Inventor: David W. Thompson
  • Filagree design furniture component
    Patent number: D601371
    Type: Grant
    Filed: April 30, 2009
    Date of Patent: October 6, 2009
    Assignee: American Signature, Inc.
    Inventor: David W. Thompson