Abstract: A method for determining the positioning in deployed position of an expandable medical device type implant, including, from a three-dimensional image of a region of interest including the vascular structure, the following steps: determination of a centreline of the vascular structure, positioning of the IMD according to an initial position, around the centreline, simulation of the final position of the IMD after deployment, as a function of the stresses exerted by the walls of the vascular structure on the IMD, the determination of the centreline consisting in placing points so as to minimise a travel time of fluid along said points between an input point and an output point, the simulation of the final position of the IMD taking account of a level of longitudinal push-pull intended to be applied to the IMD during its implantation.