Abstract: A vial adaptor (1010) may comprise a body portion (1020). The body portion includes a vial connection port (1022), a syringe connection port (1024), an access passageway (1026) between the vial connection port and the syringe connection port, and a regulation passageway (1028). The vial adaptor may further comprise an expandable and/or contractible chamber (1040) impermeable to gas and/or liquid, the regulation passageway being between the vial connection port and the chamber, and an expandable housing (1050) casing the chamber. Such a vial adaptor constitutes an improved vial adaptor.

Abstract: A luer lock adaptor including a housing defining an axis, an internal luer lock element having a threading, the internal luer lock element being located internally of the housing and being rotatably mounted thereto for rotation about the axis relative to the housing, in a manner which permits rotation of the luer lock element relative to the housing in a first rotation direction about the axis and limits rotation of the luer lock element relative to the housing in a second rotation direction about the axis, opposite to the first rotation direction, whereby the location of the internal luer lock element internally of the housing prevents manual access to the internal luer lock element for limiting rotation thereof in the first rotation direction.

Abstract: A syringe adaptor includes a body, shaped to define a body lumen, a syringe fitting at a proximal end of the body, configured to connect to a distal end of a syringe, a needle extending distally from the syringe fitting into the body lumen, a septum housing, and an elastomeric septum mounted inside the septum housing. The septum includes a proximal face, shaped to define an aperture having an aperture diameter, and a distal face. The septum is shaped to define a cavity, joined to the aperture, having a cavity diameter that is larger than the aperture diameter. The septum housing is configured to slide proximally within the body lumen such that a distal end of the needle contained in the cavity passes through the distal face of the septum. Other embodiments are also described.

Abstract: A drug mixing system including at least one receptacle port adaptor adapted to be inserted into a port of a fluid receptacle, at least one syringe adaptor adapted to be attached to a syringe and to the at least one receptacle port adaptor and at least one vial adaptor adapted for connection to a vial containing a drug and adapted for connection to the at least one syringe adaptor, the system being characterized in that at least one of the receptacle port adaptor, the at least one syringe adaptor and the at least one vial adaptor being vented to the atmosphere in a manner which prevents release to the atmosphere of possibly harmful contents of the vial in a liquid, solid or gaseous form.

Abstract: A drug mixing system including at least one receptacle port adaptor adapted to be inserted into a port of a fluid receptacle, at least one syringe adaptor adapted to be attached to a syringe and to the at least one receptacle port adaptor and at least one vial adaptor adapted for connection to a vial containing a drug and adapted for connection to the at least one syringe adaptor, the system being characterized in that at least one of the receptacle port adaptor, the at least one syringe adaptor and the at least one vial adaptor being vented to the atmosphere in a manner which prevents release to the atmosphere of possibly harmful contents of the vial in a liquid, solid or gaseous form.

Abstract: A luer lock adaptor including a housing defining an axis, an internal luer lock element having a threading, the internal luer lock element being located internally of the housing and being rotatably mounted thereto for rotation about the axis relative to the housing, in a manner which permits rotation of the luer lock element relative to the housing in a first rotation direction about the axis and limits rotation of the luer lock element relative to the housing in a second rotation direction about the axis, opposite to the first rotation direction, whereby the location of the internal luer lock element internally of the housing prevents manual access to the internal luer lock element for limiting rotation thereof in the first rotation direction.

Abstract: A protection device for a syringe having a syringe body extending along a longitudinal axis comprising, at a first end an end tip including an orifice for the passage of liquid and, at a second end, an opening for the passage of a piston provided with a maneuver head; wherein the device is adapted to at least partially cover said syringe body and is made at least in part of a radioprotective material providing protection against ionizing radiation, and wherein the device is in the form of a clamp comprising two half-jaws joined together by a hinge, which clamp includes operating means configured so that said half-jaws are moveable between: a closed operative position, in which said half-jaws are assembled to form a cylinder to at least partially cover said syringe body, and an open inactive position, adapted for the introduction and extraction of said syringe body into said half-jaws.

Abstract: A luer lock adaptor including a housing defining an axis, an internal luer lock element having a threading, the internal luer lock element being located internally of the housing and being rotatably mounted thereto for rotation about the axis relative to the housing, in a manner which permits rotation of the luer lock element relative to the housing in a first rotation direction about the axis and limits rotation of the luer lock element relative to the housing in a second rotation direction about the axis, opposite to the first rotation direction, whereby the location of the internal luer lock element internally of the housing prevents manual access to the internal luer lock element for limiting rotation thereof in the first rotation direction.

Abstract: The present disclosure relates to a device (1) for sampling and/or injection of a radioactive solution (S) in a vial (2), wherein the vial (2) comprises an opening closed by a puncturable closure member (3).