Patents Assigned to Singapore Eye Research Institute
  • Method for growth of human conjunctival tissue equivalents for research, clinical ocular surface transplantation and tissue engineering
    Patent number: 7611895
    Abstract: The invention relates to materials and methods for producing equivalents of tissues of the ocular surface, especially conjunctival tissue equivalents. The method of the invention involves biopsy of an appropriate tissue, primary culture in a certain medium, proliferative culture in a second medium, and differentiative culture in a third medium. The tissue equivalents are typically grown upon a substrate, typically amniotic membrane, which provides ease of handling as one advantage.
    Type: Grant
    Filed: April 6, 2006
    Date of Patent: November 3, 2009
    Assignee: Singapore Eye Research Institute
    Inventors: Donald Tan, Leonard Ang, Roger Beuerman
  • Method for growth of human conjunctival tissue equivalents for research, clinical ocular surface transplantation and tissue engineering
    Patent number: 7049139
    Abstract: The invention relates to materials and methods for producing equivalents of tissues of the ocular surface, especially conjunctival tissue equivalents. The method of the invention involves biopsy of an appropriate tissue, primary culture in a certain medium, proliferative culture in a second medium, and differentiative culture in a third medium. The tissue equivalents are typically grown upon a substrate, typically amniotic membrane, which provides ease of handling as one advantage.
    Type: Grant
    Filed: March 31, 2003
    Date of Patent: May 23, 2006
    Assignee: Singapore Eye Research Institute
    Inventors: Donald Tan, Leonard Ang, Roger Beuerman