Abstract: Disclosed in the present invention is a novel histone deacetylase inhibitor of benzamides and use thereof. The inhibitor has good efficacy in treating diseases caused by abnormal gene expression, such as tumors, endocrine disorders, immune system diseases, genetic diseases and nerve system diseases. The histone deacetylase inhibitor of benzamides is a compound of the following general chemical structural formula (I) or a salt thereof.
Type:
Grant
Filed:
June 26, 2012
Date of Patent:
May 26, 2015
Assignees:
Shanghai Institute of Pharmaceutical Industry, Sinopharm A-Think Pharmaceutical Co., Ltd., Sinopharm A-Think Medical and Pharmaceutical Research & Development (Beijing) Co., Ltd.
Inventors:
Jianqi Li, Qingwei Zhang, Zhidan Jia, Jiajing Wang
Abstract: Disclosed in the present invention is a novel histone deacetylase inhibitor of benzamides and use thereof. The inhibitor has good efficacy in treating diseases caused by abnormal gene expression, such as tumours, endocrine disorders, immune system diseases, genetic diseases and nerve system diseases. The histone deacetylase inhibitor of benzamides is a compound of the following general chemical structural formula (I) or a salt thereof.
Type:
Application
Filed:
June 26, 2012
Publication date:
August 7, 2014
Applicants:
Shanghai Institute of Pharmaceutical Industry, Sinopharm A-think Pharmaceutical Co., Ltd
Inventors:
Jianqi Li, Qingwei Zhang, Zhidan Jia, Jiajing Wang