Abstract: A paclitaxel pharmaceutic composition and a pharmaceutic preparation, a preparation process therefor and use thereof are provided. The paclitaxel composition contains paclitaxel as an active ingredient and hydroxypropyl methyl cellulose derivative as a carrier material. The paclitaxel preparation is in the form of an oral solid preparation. The paclitaxel composition and pharmaceutic preparation thereof can be used for the preparation of a drug for preventing and treating malignancies and relevant diseases in mammals.
Abstract: Disclosed are a ferroporphyrin solid dispersion, preparation method therefor and a pharmaceutical composition comprising the solid dispersion, wherein the weight ratio of ferroporphyrin to the carrier material in the dispersion is 1:1-1:10. The solid dispersion of the present invention masks the undesirable taste of ferroporphyrin, ameliorates irritation thereof to the digestive tract, and at the same time increases the solubility thereof and improves the bioavailability thereof.
Type:
Grant
Filed:
November 17, 2014
Date of Patent:
August 27, 2019
Assignee:
SINOTHERAPEUTICS INC.
Inventors:
Larry Yun Fang, Jiansheng Wan, Kun Li, Maojian Gu
Abstract: The present invention relates to a pharmaceutical composition comprising posaconazole and a carrier material, wherein the carrier material comprises a vinylpyrrolidone-vinyl acetate copolymer or a polymer containing ethylene glycol units. The present invention also relates to a method for the preparation of the pharmaceutical composition, a method for the prevention and/or treatment of fungal infections and related diseases in a mammal using the pharmaceutical composition, and a pharmaceutical formulation comprising the pharmaceutical composition.
Abstract: The present invention relates to a pharmaceutical composition comprising posaconazole and a carrier material, wherein the carrier material comprises a vinylpyrrolidone-vinyl acetate copolymer or a polymer containing ethylene glycol units. The present invention also relates to a method for the preparation of the pharmaceutical composition, a method for the prevention and/or treatment of fungal infections and related diseases in a mammal using the pharmaceutical composition, and a pharmaceutical formulation comprising the pharmaceutical composition.