Patents Assigned to Siolab Ltd.
  • Lipid conjugated cyclic carbonate derivatives, their synthesis, and uses
    Patent number: 8541605
    Abstract: The present disclosure provides processes for the preparation of lipid conjugated cyclic carbonate derivatives. More specifically, the present disclosure is based on the finding that reacting lipids, such as, ceramides, with N,N?-disuccinimidyl derivative, resulted in the formation of, isolatable, substituted cyclic [1,3]-dioxan-2-one and [1,3]-dioxan-2-thione compounds. These isolatable cyclic substituted compounds and derivatives thereof may be used for various applications, such as in vaccination.
    Type: Grant
    Filed: May 11, 2008
    Date of Patent: September 24, 2013
    Assignees: Siolab Ltd., Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Aaron Garzon, Jean Hildesheim