Abstract: The present invention concerns methods and reagents useful in target discovery. Specifically, the invention relates to small nucleic acid molecules capable of mediating RNA interference (RNAi), such as short interfering nucleic acid (siNA) short interfering RNA (siRNA), double-stranded RNA (dsRNA), micro-RNA (miRNA), and short hairpin RNA (shRNA) molecules and methods of target discovery using siRNA.
Type:
Application
Filed:
August 19, 2004
Publication date:
June 30, 2005
Applicant:
Sirn Therapeutics, Inc.
Inventors:
Nassim Usman, Barry Polisky, James Thompson, Leonid Beigelman