Abstract: The present invention relates to nucleic acid molecules, including antisense and enzymatic nucleic acid molecules, such as hammerhead ribozymes, DNAzymes, allozymes, aptamers, decoys and siRNA (RNAi), which modulate the expression or function of IKK genes, such as IKK-gamma, IKK-alpha, or IKK-beta, and PKR genes.
Abstract: A transcribed non-naturally occurring RNA molecule comprising a desired 10 RNA molecule, wherein the 3+ region of the RNA is able to base-pair with at least 8 bases at the 5? terminus of the same RNA molecule.