Abstract: Tetrahydrodibenzopyrans having the structure ##STR1## in which R, R.sub.1, and R.sub.2 are alkyl having from 1 to 4 carbon atoms and ophthalmologically acceptable acid addition salts thereof are effective anti-glaucoma agents, free from all but a very small amount of CNS activity, when applied topically.
Type:
Grant
Filed:
January 27, 1977
Date of Patent:
November 21, 1978
Assignee:
SISA Incorporated
Inventors:
Raj K. Razdan, Haldean C. Dalzell, Harry G. Pars
Abstract: Tetrahydrodibenzopyrans having the structure ##STR1## in which R.sub.1 is hydrogen or acetyl and R.sub.2 is alkyl having from 1 to 4 carbon atoms are effective anti-glaucoma agents, free from all but a very small amount of CNS activity, when applied topically.
Type:
Grant
Filed:
January 27, 1977
Date of Patent:
November 21, 1978
Assignee:
SISA Incorporated
Inventors:
Raj K. Razdan, Haldean C. Dalzell, Barbara Z. Terris, Harry G. Pars