Abstract: A synthesis procedure for benzazolo[3,2-a]quinolinium chloride salts and the inclusion of chloro-substituent, amino-substituent, and nitro-substituent resulting in several compounds is provided. The compounds are further used as markers due to their fluorescent properties including in hypoxic environments. Furthermore, anti-cancer screening of two BQS, namely, 7-benzyl-3-aminobenzimidazo[3,2-a]quinolinium chloride (ABQ-48: NSC D-763307) and the corresponding 7-benzyl-3-nitrobenzimidazo[3,2-a]quinolinium chloride (NBQ 48: NSC D-763303) are provided.
Type:
Application
Filed:
October 16, 2023
Publication date:
February 29, 2024
Applicant:
Sistema Universitario Ana G. Mendez, Inc.
Abstract: A synthesis procedure for benzazolo[3,2-a]quinolinium chloride salts and the inclusion of chloro-substituent, amino-substituent, and nitro-substituent resulting in several compounds is provided. The compounds are further used as markers due to their fluorescent properties including in hypoxic environments. Furthermore, anti-cancer screening of two BQS, namely, 7-benzyl-3-aminobenzimidazo[3,2-a]quinolinium chloride (ABQ-48: NSC D-763307) and the corresponding 7-benzyl-3-nitrobenzimidazo[3,2-a]quinolinium chloride (NBQ 48: NSC D-763303) are provided.
Type:
Application
Filed:
June 9, 2021
Publication date:
September 23, 2021
Applicant:
Sistema Universitario Ana G. Mendez, Inc.
Abstract: Disclosed is the synthesis procedure for benzazolo[3,2-a]quinolinium chloride salts and the inclusion of chloro-substituent, amino-substituent, and nitro-substituent resulting in several compounds. The compounds are further used as markers due to their fluorescent properties including in hypoxic environments. This disclosure further describes anti-cancer screening of two BQS, namely, 7-benzyl-3-aminobenzimidazo[3,2-a]quinolinium chloride (ABQ-48: NSC D-763307) and the corresponding 7-benzyl-3-nitrobenzimidazo[3,2-a]quinolinium chloride (NBQ 48: NSC D-763303).
Type:
Application
Filed:
April 20, 2020
Publication date:
August 20, 2020
Applicant:
Sistema Universitario Ana G. Mendez, Inc.
Abstract: Disclosed is the synthesis procedure for benzazolo[3,2-a]quinolinium chloride salts and the inclusion of chloro-substituent, amino-substituent, and nitro-substituent resulting in several compounds. The compounds are further used as markers due to their fluorescent properties including in hypoxic environments. This disclosure further describes anti-cancer screening of two BQS, namely, 7-benzyl-3-aminobenzimidazo[3,2-a]quinolinium chloride (ABQ-48: NSC D-763307) and the corresponding 7-benzyl-3-nitrobenzimidazo[3,2-a]quinolinium chloride (NBQ 48: NSC D-763303).
Type:
Application
Filed:
April 20, 2020
Publication date:
August 6, 2020
Applicant:
Sistema Universitario Ana G. Mendez, Inc.
Abstract: Disclosed is the synthesis procedure for benzazolo[3,2-a]quinolinium chloride salts and the inclusion of chloro-substituent, amino-substituent, and nitro-substituent resulting in several compounds. The compounds are further used as markers due to their fluorescent properties including in hypoxic environments. This disclosure further describes anti-cancer screening of two BQS, namely, 7-benzyl-3-aminobenzimidazo[3,2-a]quinolinium chloride (ABQ-48: NSC D-763307) and the corresponding 7-benzyl-3-nitrobenzimidazo[3,2-a]quinolinium chloride (NBQ 48: NSC D-763303).
Type:
Application
Filed:
February 13, 2018
Publication date:
August 2, 2018
Applicant:
Sistema Universitario Ana G. Mendez, Inc.
Abstract: Disclosed is the synthesis procedure for benzazolo[3,2-a]quinolinium chloride salts and the inclusion of chloro-substituent, amino-substituent, and nitro-substituent resulting in several compounds. The compounds are further used as markers due to their fluorescent properties including in hypoxic environments. This disclosure further describes anti-cancer screening of two BQS, namely, 7-benzyl-3-aminobenzimidazo[3,2-a]quinolinium chloride (ABQ-48: NSC D-763307) and the corresponding 7-benzyl-3-nitrobenzimidazo[3,2-a]quinolinium chloride (NBQ 48: NSC D-763303).
Type:
Application
Filed:
September 17, 2015
Publication date:
January 11, 2018
Applicant:
SISTEMA UNIVERSITARIO ANA G. MENDEZ, INC.
Abstract: Disclosed is the synthesis procedure for benzazolo[3,2-a]quinolinium chloride salts and the inclusion of chloro-substituent, amino-substituent, and nitro-substituent resulting in several compounds. The compounds are further used as markers due to their fluorescent properties including in hypoxic environments. This disclosure further describes anti-cancer screening of two BQS, namely, 7-benzyl-3-aminobenzimidazo[3,2-a]quinolinium chloride (ABQ-48: NSC D-763307) and the corresponding 7-benzyl-3-nitrobenzimidazo[3,2-a]quinolinium chloride (NBQ 48: NSC D-763303).
Type:
Application
Filed:
September 17, 2015
Publication date:
March 23, 2017
Applicant:
SISTEMA UNIVERSITARIO ANA G. MENDEZ, INC.
Abstract: Semiconductor materials offer several potential benefits as active elements in the development of harvesting-energy conversion technologies. In particular, lead selenide (PbSe) semiconductors have been used and proposed to design solar energy harvesting devices, IR sensors, FET devices, amongst others. The present disclosure provides a simple, low cost synthesis of lead selenide using benzoic acid as the capping ligand in an opened environment. The use of an aromatic ligand, and mores specifically benzoic acid, provides robustness and more durability to the lead selenide, and therefore prevents the lead selenide from breaking or cracking easily. Also the aromatic ligand prevents the degradation and oxidation of the lead selenide, without affecting any of the lead selenide electronic and chemical characteristics.
Type:
Application
Filed:
November 26, 2014
Publication date:
November 19, 2015
Applicant:
Sistema Universitario Ana. G Méndez, Inc.
Inventors:
Mitk'El B. Santiago Berríos, Weyshla A. Rodríguez Rodríguez
Abstract: An automated email virus detection and control scheme using attachment chain tracing (ACT) technique is provided. Based on conventional epidemiology, ACT detects virus propagation by identifying the existence of transmission chains in the network. It uses contact tracing to find epidemiological links between hosts. A soft-quarantine scheme controls virus propagation by detecting and quarantining without virus signature information. A progressive immunization strategy uses transmission chain information to guide the immunization process.
Type:
Grant
Filed:
October 16, 2006
Date of Patent:
September 24, 2013
Assignee:
Sistema Universitario Ana G. Mendez, Inc.