Abstract: A method is provided that non-coding RNA profiles can be exploited as a means of monitoring, assessing, comparing, establishing and/or determining certain cell characteristics and/or profiles. Accordingly, the use of non-coding RNA molecules for characterising and/or profiling cells is provided.
Abstract: There is disclosed a method comprising the steps of: carrying out a plurality of expression assays, each expression assay comprising the steps of: carrying out an intervention on a biological system, measuring an expression profile of non-coding RNAs in the biological system resulting from the intervention, and storing an expression data set derived from the measured expression profile, the said expression assays concerning either or both a plurality of different interventions and a plurality of different biological systems; and analysing the resulting expression data sets to determine correlations between the effect on the expression profile of non-coding RNAs of the respective intervention in groups of two or more expression assays concerning either or both different interventions or different biological systems.
Type:
Application
Filed:
July 6, 2015
Publication date:
January 7, 2016
Applicant:
SISTEMIC SCOTLAND LIMITED
Inventors:
Jacinto ESTIBEIRO, John Gordon, Christopher Robert Hillier, Vincent O'Brien
Abstract: There is disclosed a method comprising the steps of: carrying out a plurality of expression assays, each expression assay comprising the steps of: carrying out an intervention on a biological system, measuring an expression profile of non-coding RNAs in the biological system resulting from the intervention, and storing an expression data set derived from the measured expression profile, the said expression assays concerning either or both a plurality of different interventions and a plurality of different biological systems; and analysing the resulting expression data sets to determine correlations between the effect on the expression profile of non-coding RNAs of the respective intervention in groups of two or more expression assays concerning either or both different interventions or different biological systems.
Type:
Grant
Filed:
January 19, 2010
Date of Patent:
July 7, 2015
Assignee:
Sistemic Scotland Limited
Inventors:
Jacinto Peter Estibeiro, John Francis Gordon, Christopher Robert Hillier, Vincent O'Brien
Abstract: The present invention concerns the finding that non-coding RNA profiles can be exploited as a means of monitoring, assessing, comparing, establishing and/or determining certain cell characteristics and/or profiles. Accordingly, the invention provides the use of non-coding RNA molecules for characterising and/or profiling cells.