Abstract: An ultrasound transducer comprises a sheath body constructed from a nonconductive material. The sheath body is configured to be installed over a medical device. A piezoelectric copolymer transducer is held snugly against the medical device by the sheath body when the ultrasound transducer is installed over the medical device. The piezoelectric copolymer transducer transduces incident ultrasound signals into corresponding electric signals. A ground conductor is coupled to a first surface of the piezoelectric copolymer transducer. A signal conductor is coupled to a second surface of the piezoelectric copolymer transducer and conducts the corresponding electric signals to a proximal end of the medical device.

Abstract: A drug-infusing device is implanted into a body cavity such as a bladder. The device is implanted in an uninflated, low profile state. After insertion into the body cavity, the device is filled with a substance, such as a drug, and assumes an increased profile. After the device is filled, it is allowed to float freely within the body cavity. Alternatively, the device can be tethered to a wall of the body cavity. The device delivers the drug at a controlled rate over an extended period of time. In order to deliver the drug at a controlled rate, the device preferably has a pressure-responsive valving member. The flow resistance of the valving member is responsive to the pressure at which the drug is stored within the infusing device. The resistance of the valving member decreases as the pressure within the infusing device decreases, thereby providing a resultant controlled flow rate.

Abstract: A drug-infusing device is implanted into a body cavity such as a bladder. The device is implanted in an uninflated, low profile state. After insertion into the body cavity, the device is filled with a substance, such as a drug, and assumes an increased profile. After the device is filled, it is allowed to float freely within the body cavity. Alternatively, the device can be tethered to a wall of the body cavity. The device delivers the drug at a controlled rate over an extended period of time. In order to deliver the drug at a controlled rate, the device preferably has a pressure-responsive valving member. The flow resistance of the valving member is responsive to the pressure at which the drug is stored within the infusing device. The resistance of the valving member decreases as the pressure within the infusing device decreases, thereby providing a resultant controlled flow rate.

Abstract: A delivery device and method for delivering a medical device, such as an infuser, into a body cavity are disclosed. The delivery device includes an ejector tube which slidably extends through a handle. The ejector tube is configured for easy insertion through the urethra into the bladder. A hollow inner tube is located within the ejector tube and includes luer fittings at its distal and proximal ends. The luer fitting at the proximal end of the inner tube is coupled to the handle. Movement of the ejector tube relative to the inner tube causes the distal luer fitting to be withdrawn within the ejector tube and can be used to force an infuser attached to the distal luer fitting from the distal luer fitting. Materials can be transported to the infuser from the proximal luer fitting through the inner tube and out through the distal luer connector.

Abstract: A surgical instrument comprising a probe for insertion into the body of a host and for manipulating the tissues of the host, the probe including an ultrasound transducer element for locating and positioning the probe within the body of the host; and a method for manipulating the tissues of a host using the surgical instrument.

Abstract: Oxybutynin chloride formulations having increased stability at body temperature, even at high concentrations. These formulations comprise oxybutynin chloride at a pH of between 3.0 and 5.0, and may include a buffer capable of providing adequate buffering capacity in this range. The OC solutions can be placed in an infuser device for treatment of bladder dysfunction.

Abstract: A surgical device is comprised of a probe adapted for insertion into a patient. The probe has a means for manipulating tissue within a zone of manipulation. The probe also has a first receiver which is disposed within the zone of manipulation. The first receiver responds to receipt of a radiated signal by generation of a first receiver signal indicating a strength at which the radiated signal is received. A means for analyzing the first receiver signal determines a measure of manipulation to the tissue within the zone of manipulation. In one embodiment, the first receiver is disposed at the tip of the probe. In another embodiment, the means for manipulating removes energy from the tissue. In yet another embodiment, the means for manipulating adds energy to the tissue so as to alter the tissue. Optionally, the means for analyzing accumulates a set of values of the first receiver signal over time in order to determine the measure of manipulation. A scanner generates the radiated signal.