Abstract: The invention provides compositions containing cargo molecules attached to elements that improve the function of the cargo molecules in the body of a subject. The compositions are useful for therapeutic and diagnostic purposes. Furthermore, the invention outlines ways in which these compositions can be produced; the core molecule can be functionalized, via bioorthogonal click chemistry, in such a way as to impart modular characteristics. This functionalization simultaneously allows for loading of biologically relevant cargo and provides stabilization to the overall structure of the molecule.
Type:
Grant
Filed:
April 27, 2021
Date of Patent:
June 14, 2022
Assignee:
Sixfold Bioscience Ltd.
Inventors:
James Luke Rushworth, George William Foot, Anna Perdrix Rosell, Zuzanna Aleksandra Brzosko
Abstract: The invention provides compositions for delivery of cargo to cells. The invention also provides compositions that bind multiple agents simultaneously. The compositions are useful as therapeutics. Methods of using the compositions are also provided.
Type:
Application
Filed:
February 19, 2021
Publication date:
July 15, 2021
Applicant:
Sixfold Bioscience Ltd.
Inventors:
George William Foot, Anna Perdrix Rosell, Zuzanna Aleksandra Brzosko
Abstract: The invention provides compositions for delivery of cargo to cells. The invention also provides compositions that bind multiple agents simultaneously. The compositions are useful as therapeutics. Methods of using the compositions are also provided.
Type:
Grant
Filed:
March 1, 2019
Date of Patent:
April 20, 2021
Assignee:
Sixfold Bioscience Ltd.
Inventors:
George Foot, Anna Perdrix Rosell, Zuzanna Brzosko